Table 1.
Previous reports on association between BMD and mortality in ESRD patients
| References | Location | No. of patients | Sex | Age (years) (mean/ median) | Dialysis modality | Design | Follow-up (years) | BMD sites | Measurement method | Outcomes | Factors controlled for in multivariate analysis | Outcomes associated with |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Taal et al. [18] | UK | 88 | F/M | 51–70 | HD | Prospective observational | 3.5 | Spine, hip | Central-DXA | All-cause mortality | Age, Ca × P and previous allograft | Hip |
| Matsubara et al. [7] | Sweden | 277 | F/M | 55 | HD/PD | Prospective observational | 5 | Total | Whole-DXA | All-cause and CVD mortality | Age, sex, DM, CVD, hsCRP, phosphate, Ca × P and SGA | Total |
| Park et al. [6] | Sweden | 361 | F/M | 53 | HD/PD | Prospective observational | 5 | Total | Whole-DXA | All-cause mortality | Age, fat body mass and SGA | Total |
| Disthabanchong et al. [20] | Thailand | 83 | F/M | 57 | HD | Prospective observational | 5 | Spine, hip | Central-DXA | All-cause mortality | Age, Davies score, dyslipidaemia, albumin and CAC score | Hip |
| Chen et al. [66] | Sweden | 231 | F/M | 56 | HD/PD | Prospective observational | 5 | Spine | Whole-DXA/CT | All-cause mortality | Age, sex, diabetes, CVD, hsCRP and SGA | Spine (VBD by CT) |
| Yap et al. [67] | Australia | 58 | F/M | 58–65 | HD/PD | Prospective observational | 6 | Spine/FN | Central-DXA/pQCT | All-cause mortality | Age, sex, transplant status, albumin, PTH, phosphate, dialysis duration, diabetes and smoking | FN |
| Orlic et al. [19] | Croatia | 134 | F/M | 59 | HD | Prospective observational | 4 | Spine, hip, forearm | Central-DXA | All-cause mortality | Age and sexa (used as a Z-score) | Forearm |
| Iseri et al. [17] | Sweden | 426 | F/M | 56 | HD/PD | Prospective observational | 5 | Total, head, arms, legs, trunk, hip, pelvis, spine | Whole-DXA | All-cause and CVD mortality | Framingham CVD risk score, SGA, %HGS, albumin, hsCRP, LBMI, recruitment year | Total, head, pelvis (and leg) |
DM, diabetes mellitus; FN, femoral neck; %HGS, percent handgrip strength; hsCRP, high-sensitivity C-reactive protein; LBMI, lean body mass index; SGA, subjective global assessment. aOutcomes significantly associated with.