Table 2.

Clinical features, treatment, outcome, and follow-up of 16 patients with classic adamantinoma

Patient number	Age gender	Initial localization lesion	Previous surgery	Initial diagnosis	Initial treatment	Surgical margins	Final diagnosis	LR	Distant metastasis	Other treatment	Outcome	FU months
1	30/M	Tibia, multiple	None	AD	Resection +Recycled bone	Wide	AD				CDF	184
2	19/F	Tibia and fibula	Curettage	AD	Resection +Allograft, fibular resection	Wide	AD				CDF	161
3	46/M	Tibia, single	Curettage	AD	Resection +Allograft	Wide	AD				CDF	18
4	17/F	Tibia and fibula	None	AD	Resection +Allograft, fibular resection	Wide	AD				CDF	18
5	42/F	Tibia, single	None	AD	Resection +Allograft	Wide	AD				CDF	175
6	27/M	Tibia, single	Curettage	AD	Resection +Allograft	Wide	AD	84 months	106 m, lung	Amputation after LR	DOD	126
7	24/F	Tibia, single	None	AD	Cortical resection + Allograft	Marginal	AD				CDF	19
8	33/M	Tibia, single	None	AD	Cortical resection + Allograft	Marginal	AD				CDF	97
9	23/M	Tibia and fibula	Curettage	OFD	Curettage + Bone grafting	Intralesional	AD	9 months		Amputation after LR	NED	142
10	38/F	Tibia, single	Curettage	AD	Resection +Allograft	Wide	AD				CDF	125
11	33/M	Tibia,multiple	None	AD	Resection +Allograft	Marginal	AD				CDF	84
12	16/F	Fibula, single	None	AD	Resection	Wide	AD			84 m, new developed tibia lesion resection	NED	120
13	36/M	Tibia,multiple	Curettage	AD	Resection +Allograft	Marginal	AD	19 months	20 m, lung	Amputation after LR	DOD	88
14	20/F	Tibia,multiple	None	AD	Resection +Allograft	Wide	AD				CDF	84
15	18/M	Tibia and fibula	None	AD	BKA	Wide	AD				CDF	54
16	54/F	Tibia, single	Curettage	AD	Resection +Prosthesis	Wide	AD				CDF	45

BKA below the knee amputation, CDF continued to be disease-free, DOD dead of disease, F female, FU follow-up, LR local recurrence, Lung lung metastasis, M male, NED no evidence of disease