Table 3.
Odds ratio of triple negative breast cancer in relation to methylation levels at cg06588802 in LINC00299, all ages.
| Methylation level | ||||||
|---|---|---|---|---|---|---|
| Quartile (Q) | Mean | Cases n | Controls n | ORa | 95% CI | P value |
| Totalb | 154 | 159 | ||||
| Q1 (0.289–0.388) | 0.354 | 34 | 41 | 1.00 | Baseline | |
| Q2 (0.389–0.420) | 0.406 | 26 | 39 | 0.80 | 0.37–1.71 | 0.56 |
| Q3 (0.421–0.461) | 0.441 | 51 | 40 | 1.51 | 0.77–2.98 | 0.23 |
| Q4 (0.462–0.558) | 0.486 | 43 | 39 | 1.27 | 0.61–2.63 | 0.53 |
| Trend (across quartiles) | 0.14 | |||||
| Trend (across methylation ratio) | 0.082 | |||||
OR odds ratio, CI confidence interval.
aConditional matched analysis [year of entry to study, age at entry, days blood in post before processing, and cancer-free years (time at risk)], adjusted for smoking status.
bIncluding twelve participants with prior cancer (that is not breast cancer).