Table 5.
Multiple regression analysis showing the association between parental %FM measured early in pregnancy with offspring plasma growth hormone levels at age 2 years.
Growth Hormone | β | SE | 95% CI | Pr2 | p-value |
---|---|---|---|---|---|
Girls (n=30) | |||||
Paternal %FM | −0.08 | 0.03 | −0.13, −0.02 | 0.23 | 0.008 |
Maternal %FM | 0.06 | 0.02 | 0.01, 0.11 | 0.19 | 0.017 |
Boys (n=37) | |||||
Paternal %FM | −0.04 | 0.02 | −0.07, −0.01 | 0.14 | 0.023 |
Maternal %FM | −0.01 | 0.01 | −0.03, 0.02 | 0.01 | 0.564 |
IGF-1 | |||||
Girls | |||||
Paternal %FM | 0.35 | 0.77 | −1.23–1.93 | 0.01 | 0.651 |
Maternal %FM | 1.42 | 0.69 | −0.01–2.84 | 0.14 | 0.051 |
Boys | |||||
Paternal %FM | 1.23 | 0.45 | 0.03–2.16 | 0.19 | 0.011 |
Maternal %FM | 0.02 | 0.37 | −0.67–0.71 | 0.00 | 0.946 |
IGFBP-3 | |||||
Girls | |||||
Paternal %FM | 0.00 | 0.03 | −0.05–0.06 | 0.00 | 0.889 |
Maternal %FM | 0.03 | 0.02 | −0.02–0.08 | 0.07 | 0.181 |
Boys | |||||
Paternal %FM | 0.01 | 0.02 | 0.02–0.05 | 0.02 | 0.388 |
Maternal %FM | 0.00 | 0.01 | −0.02–0.03 | 0.00 | 0.855 |
%FM= percent fat mass, IGF-1= Insulin-like growth factor 1, IGFBP-3= Insulin-like growth factor binding protein 3, SE=standard error; Pr2=square partial correlation.