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. 2020 Jul 16;10:11765. doi: 10.1038/s41598-020-68797-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Exemplary cross-sectional images of three subjects (A₁/A₂, B₁/B₂, C₁/C₂) from the study population illustrating agreement of CT and MRI derived muscle fat infiltration measurements. CT and MRI muscle fat infiltration were calculated as mean radiodensity in Hounsfield units (HU) and proton density fat fraction (MRI^PDFF) in percent (%), respectively. Based on the correlation between CT and MRI muscle fat infiltration, a linear regression model was fit to calculate CT derived fat fraction (CT^FF) from mean radiodensity based on the corresponding MRI^PDFF values. CT computed tomography, MRI magnetic resonance imaging.