Table 2.
Antifungal activities of compounds against Yeasts (MIC, MIC50, MFC μM).
| Strain | pH | 3,6NH2 | 3,6-PIRAMICAR | Fluconazole | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MIC50 | MIC | MFC | MIC50 | MIC | MFC | MIC50 | MIC | MFC | ||
| C. albicans | 7.0 | > 250 | > 250 | > 250 | > 250 | > 250 | > 250 | 7.46 ± 3.69 | 125 | 250 |
| 5.5 | 98.26 ± 22.52 | > 250 | > 250 | 35.26 ± 9.26 | 250 | 250 | 7.71 ± 2.81 | > 250 | > 250 | |
| 4.0 | 113.25 ± 12.95 | > 250 | > 250 | 106 ± 13.78 | 250 | > 250 | 5.89 ± 2.09 | > 250 | > 250 | |
| C. glabrata | 7.0 | > 250 | > 250 | > 250 | > 250 | > 250 | > 250 | 19.99 ± 5.45 | 62.5 | 125 |
| 5.5 | > 250 | > 250 | > 250 | > 250 | > 250 | > 250 | 229.6 ± 28.96 | > 250 | > 250 | |
| 4.0 | 63.22 ± 8.14 | 125 | 250 | 30.88 ± 6.56 | 62.5 | 125 | > 250 | > 250 | > 250 | |
| C. krusei | 7.0 | > 250 | 250 | > 250 | > 250 | > 250 | > 250 | 8.15 ± 3.13 | 62.5 | 125 |
| 5.5 | 82.12 ± 9.24 | > 250 | > 250 | 78.11 ± 8.24 | > 250 | > 250 | 8.75 ± 4.65 | 250 | > 250 | |
| 4.0 | 31.94 ± 7.86 | 125 | 250 | 10.05 ± 3.54 | 31.25 | 62.5 | 140.01 ± 26.05 | 250 | > 250 | |