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. 2020 Jul 17;15(7):e0235985. doi: 10.1371/journal.pone.0235985

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© 2020 Yarullina et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — Carbachol-evoked contractions of descending colon strips from patients with CC (A, B). Dose-response effects of carbachol on the amplitude of contraction of circular (Aa) and longitudinal (Ba) muscle strips in the control (white squares) and the CC groups (white circles). The amplitudes were normalized by the weight of specimens in each experiment. * p < 0.05; ** p < 0.01. Examples of contractions of circular (Ab) and longitudinal (Bb) muscle strips in the control and the CC groups in response to the application of carbachol (10 μM).