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. 2020 Jul 17;8(10):e1264–e1272. doi: 10.1016/S2214-109X(20)30308-9

Table 2.

Benefits and risks of sustaining routine childhood immunisation at the national level

Deaths averted by vaccination (95% UI) Excess COVID-19 deaths (95% UI) Benefit–risk ratio (95% UI)
Algeria 18 164 (11 750–28 146) 268 (29–794) 69 (10–234)
Angola 26 156 (18 377–36 792) 146 (24–434) 180 (28–598)
Benin 7285 (4817–11 246) 78 (8–228) 95 (14–311)
Botswana 989 (646–1511) 15 (2–43) 70 (11–233)
Burkina Faso 14 103 (9626–20 955) 180 (20–534) 80 (13–259)
Burundi 8640 (5946–12 784) 79 (13–238) 110 (19–367)
Cameroon 13 031 (8735–19 862) 176 (20–519) 75 (11–249)
Cape Verde 148 (85–251) 3 (0–9) 52 (6–176)
Central African Republic 2353 (1585–3513) 20 (3–60) 119 (21–392)
Chad 9016 (5998–13 984) 98 (10–288) 94 (11–310)
Comoros 420 (267–661) 7 (1–22) 58 (7–197)
Congo (Brazzaville) 3370 (2366–4919) 21 (3–63) 160 (19–515)
Côte d'Ivoire 19 401 (12 712–28 863) 194 (20–571) 102 (16–339)
Democratic Republic of the Congo 61 538 (41 399–92 956) 563 (88–1674) 111 (18–371)
Djibouti 273 (173–435) 5 (1–14) 58 (8–203)
Egypt 24 593 (11 655–48 336) 412 (54–1221) 60 (6–216)
Equatorial Guinea 360 (231–564) 4 (0–13) 83 (12–273)
Eritrea 2103 (1380–3152) 29 (4–88) 74 (9–245)
eSwatini 346 (180–603) 9 (1–28) 38 (4–136)
Ethiopia 60 854 (38 286–95 401) 866 (100–2558) 73 (10–243)
Gabon 866 (554–1360) 8 (1–25) 105 (17–358)
Gambia 2208 (1560–3107) 39 (6–117) 58 (10–189)
Ghana 18 589 (12 358–26 534) 219 (32–658) 86 (14–281)
Guinea 9307 (6339–13 372) 121 (17–362) 78 (11–255)
Guinea-Bissau 1355 (960–1912) 12 (1–36) 113 (18–379)
Kenya 20 030 (12 691–31 736) 241 (38–720) 86 (13–292)
Lesotho 829 (536–1263) 15 (2–43) 57 (8–195)
Liberia 3965 (2913–5689) 34 (4–101) 118 (17–381)
Libya 2323 (1517–3463) 34 (5–103) 70 (11–230)
Madagascar 14 293 (9228–22 263) 136 (21–405) 107 (16–359)
Malawi 8923 (5398–14 737) 131 (20–393) 69 (10–232)
Mali 13 302 (9259–18 971) 144 (17–426) 94 (14–308)
Mauritania 2720 (1905–4119) 30 (3–90) 91 (13–310)
Mauritius 260 (177–391) 4 (1–11) 71 (11–230)
Morocco 7273 (3698–13 837) 221 (26–657) 34 (4–124)
Mozambique 20 206 (13 487–30 366) 208 (33–624) 98 (14–317)
Namibia 1179 (768–1812) 19 (2–56) 63 (9–214)
Niger 21 835 (15 854–30 867) 262 (30–776) 85 (13–278)
Nigeria 89 167 (61 172–133 594) 942 (98–2773) 96 (16–316)
Rwanda 8061 (5274–12 053) 87 (14–260) 94 (15–318)
São Tomé and Príncipe 120 (72–186) 1 (0–4) 91 (12–296)
Senegal 11 306 (7856–15 866) 250 (37–758) 46 (6–154)
Seychelles 34 (23–50) 0 (0–1) 74 (10–245)
Sierra Leone 6891 (5096–9376) 86 (11–256) 81 (12–266)
Somalia 9697 (6695–14 275) 102 (11–300) 96 (16–319)
South Africa 18 844 (12 575–28 607) 310 (36–920) 62 (10–209)
South Sudan 3176 (1716–5251) 34 (5–102) 93 (11–322)
Sudan 22 338 (13 975–34 110) 334 (49–1003) 68 (10–231)
Tanzania 36 630 (23 570–56 036) 584 (87–1757) 64 (8–209)
Togo 4933 (3206–7819) 56 (6–164) 90 (13–307)
Tunisia 1854 (723–3626) 54 (8–163) 35 (3–128)
Uganda 20 906 (12 346–34 358) 246 (39–734) 87 (12–299)
Zambia 11 042 (7453–16 810) 121 (19–361) 93 (13–312)
Zimbabwe 7759 (5269–11 124) 94 (14–284) 83 (12–278)

The benefit–risk ratio estimates (median estimates and 95% UIs) show the child deaths averted by sustaining routine childhood immunisation in the African countries per COVID-19 death attributable to excess severe acute respiratory syndrome coronavirus 2 infections acquired through visiting routine vaccination service delivery points. The combined impact of routine childhood immunisation is shown, including all vaccinations in EPI-1, EPI-2, and EPI-3. EPI=Expanded Programme on Immunization. UI=uncertainty interval.