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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Curr Genet. 2020 Mar 30;66(4):813–822. doi: 10.1007/s00294-020-01068-w

Figure 5. Impact of lowered guanylate kinase activity on replicative lifespan.

Figure 5.

A. Lifespan curves for haploid yeast (BY4741) in wild-type or mutated guk1–1 genetic background. B. Lifespan curves for haploid yeast (BY4741) in wild-type or mutated guk1–1 genetic background, together with wild-type strain under MPA treatment. N = 400 cells for the wild-type DMSO condition, pooled from four independent experiments of 100 cells each; N = 200 cells for the mutated guk1–1 strain in DMSO condition, pooled from two independent experiments of 100 cells each; N = 300 cells for wild-type strain under MPA treatment, pooled from three independent experiments of 100 cells each. Colored numbers next to the lifespan curves indicate the average replicative lifespan values corresponding to the lifespan curve matching its color.