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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Curr Genet. 2020 Mar 30;66(4):813–822. doi: 10.1007/s00294-020-01068-w

Table 1.

Summary of lifespans and log-rank test results.

Condition 1 Condition 1 Mean Lifespan (Generations) Condition 2 Condition 2 Mean Lifespan (Generations) Percent Change p-value obtained from log-rank test
BY4741-DMSO 23.39 BY4741-Guanine 22.7 −2.949978623 0.9034
BY4741-DMSO 23.39 BY4741-MPA 28.553 22.0735357 1.43E-09
BY4741-DMSO 23.39 BY4741-MPA-Guanine 24.183 3.390337751 0.0463
BY4741-DMSO 23.39 ΔHXK2-DMSO 26.845 14.77126977 6.60E-04
ΔHXK2-DMSO 26.845 ΔHXK2-Guanine 27.6 2.812441795 0.45
ΔHXK2-DMSO 26.845 ΔHXK2-MPA 31.35 16.78152356 0.0000269
BY4741-MPA 28.553 ΔHXK2-MPA 31.35 9.795818303 0.0039
BY4741-DMSO 23.39 ΔTOR1-DMSO 28.805 23.1509192 4.27E-08
ΔTOR1-DMSO 28.805 ΔTOR1-Guanine 28.935 0.451310536 0.87
ΔTOR1-DMSO 28.805 ΔTOR1-MPA 32.525 12.91442458 0.000634
BY4741-MPA 28.553 ΔTOR1-MPA 32.525 13.91097258 2.40E-06
BY4741-DMSO 23.39 ΔUBR2-DMSO 28.8 23.12954254 2.32E-13
ΔUBR2-DMSO 28.8 ΔUBR2-Guanine 27.28 −5.277777778 0.0147
ΔUBR2-DMSO 28.8 ΔUBR2-MPA 31.5 9.375 0.0122
BY4741-MPA 28.553 ΔUBR2-MPA 31.5 10.32115715 2.35E-04
BY4741-Guanine 22.7 ΔUBR2-Guanine 27.28 20.17621145 7.99E-08
BY4741-DMSO 23.39 ΔPRE9-DMSO 23.005 −1.646002565 0.5019
ΔPRE9-DMSO 23.005 ΔPRE9-MPA 27.84 21.01717018 0.0000684
BY4741-MPA 28.553 ΔPRE9-MPA 27.84 −2.497110636 0.1524
BY4741-DMSO 23.39 BY4741-MPA(0–24) 24.37 4.189824711 0.0013
BY4741-DMSO 23.39 BY4741-MPA(24+) 25.55 9.23471569 0.0066
BY4741-DMSO 23.39 BY4741-MPA(24–30) 23.755 1.560495938 0.2429
BY4741-MPA 28.553 BY4741-MPA(0–24) 24.37 −14.64994922 0.0436
BY4741-MPA 28.553 BY4741-MPA(24+) 25.55 −10.51728365 0.0122
BY4741-MPA 28.553 BY4741-MPA(24–30) 23.755 −16.80383848 4.83E-04
BY4741-MPA(0–24) 24.37 BY4741-MPA(24–30) 23.755 −2.523594584 0.15
BY4741-MPA(0–24) 24.37 BY4741-MPA(24+) 25.55 4.842018876 0.66
BY4741-MPA(24+) 25.55 BY4741-MPA(24–30) 23.755 −7.025440313 0.279
BY4741-DMSO 23.39 guk1–1-DMSO 28.3 20.99187687 2.83E-05
BY4741-MPA 28.553 guk1–1-DMSO 28.3 −0.886071516 0.1155