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. Author manuscript; available in PMC: 2021 Jan 15.
Published in final edited form as: Clin Cancer Res. 2020 Mar 27;26(14):3629–3640. doi: 10.1158/1078-0432.CCR-19-3283

Figure 1:

Figure 1:

(A) Oncoprint displaying recurrent somatic mutations (genes mutated in >1 sample) and frequent copy number variants (CNVs) in the MSK-IMPACT cohort. Copy number variants (CNVs) CNVs are mostly found in cases with a high AJCC stage. The most frequent MiTF fusion gene was TFE3. (B) TMB in merged MSK-TCGA exomes compared to other TCGA-RCC cohorts. (C) Tumor mutation burden of tRCC is centered around a median value of 0.8 non-synonymous mutations per megabase, with two outlier cases. Mann-Whitney U tests were used for pairwise TMB comparisons between RCC subtypes.