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. 2020 May 18;14(8):2179–2196. doi: 10.1038/s41396-020-0679-2

Table 2.

Simulation and calculation results under the exposure of non-antibiotic pharmaceuticals.

Condition Kμ* Amplify factor of Kμ* μ Kd* Amplify factor of Kd* d Stability time (h)a
Control 0.157 1 1.75 × 10−9 0.936 1 0.0117 178
Ibuprofen 0.856 5.5 9.54 × 10−9 1.109 1.1848 0.0139 148
Naproxen 1.230 7.8 1.37 × 10−8 0.946 1.0107 0.0118 153
Gemfibrozil 2.937 18.7 3.27 × 10−8 0.955 1.0203 0.0119 152
Diclofenac 1.576 10.0 1.76 × 10−8 1.161 1.2404 0.0145 134
Propranolol 2.984 19.0 3.33 × 10−8 1.193 1.2746 0.0149 131
Iopromide 0.395 2.5 4.41 × 10−9 0.969 1.0353 0.0121 171
Combined effect Product 1.9998 0.0233 105

aThe time reaching 95% of the final theoretical value.