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. 2020 Jul 12;13:2495–2504. doi: 10.2147/DMSO.S260901

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© 2020 Zhang and Zhang.

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EGCG alleviates endothelial dysfunction of hyperglycemia-induced vascular endothelial cells. (A) The ROS levels in HG-treated HUVECs affected by EGCG was detected by ROS ELISA assay. *P<0.05 and ***P<0.001 vs Normal group. ^###P<0.001 vs HG group. ^∆P<0.05 and ^∆∆∆P<0.001 vs EGCG10μM group. ^&P<0.05 vs EGCG20μM group. (B) The NO levels in HG-treated HUVECs affected by EGCG was detected by ROS ELISA assay. ***P<0.001 vs Normal group. ^##P<0.01 and ^###P<0.001 vs HG group. ^∆∆∆P<0.001 vs EGCG10μM group. ^&&P<0.01 vs EGCG20μM group. (C) The expression of p-eNOS and eNOS in HG-treated HUVECs affected by EGCG was detected by Western blot analysis. *P<0.05 and ***P<0.001 vs Normal group. ^#P<0.05, ^##P<0.01 and ^###P<0.001 vs HG group. ^∆∆∆P<0.001 vs EGCG10μM group. (D) The ROS levels in HG-treated HUVECs affected by EGCG was detected by fluorometric ROS assay.