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. 2020 Jul 12;13:2495–2504. doi: 10.2147/DMSO.S260901

Figure 8.

Figure 8

EGCG alleviates the apoptosis of hyperglycemia-induced vascular endothelial cells by activating the PI3K/AKT pathway. (A) The apoptosis of HG-treated HUVECs affected by EGCG and LY294002 was analyzed by TUNEL assay. (B) The expression of bcl2, bax, cleaved-caspase3 and caspase3 in HG-treated HUVECs affected by EGCG and LY294002 was detected by Western blot analysis. *P<0.05, **P<0.01 and ***P<0.001 vs Normal group. ##P<0.01 and ###P<0.001 vs HG group. ∆∆P<0.01 vs EGCG50μM group.