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. 2020 Jun 6;10(4):569–587. doi: 10.1007/s13555-020-00407-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 3 — bFGF downstream mediators Ras and PI3K activate miR-20a expression, which in turn inhibits the expression of the TGFβ receptor complex (ALK5 and TGFBR2) and SARA, thus blocking the Smad2 and Smad3 activation, which plays an important role in the development of fibroproliferative disorders