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. 2020 Jul 17;11:84. doi: 10.1186/s13244-020-00888-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Gliomatosis cerebri. Conventional MRI: a, b Axial FLAIR and post-contrast T1W sequences, showing diffuse infiltrative non-enhancing deep white matter lesion. Multiparametric MRI: c ADC map demonstrates no areas of low ADC. d However, PWI shows a focal area of slightly raised perfusion in the right frontal centrum semiovale (arrow) compared to normal-appearing white matter. e, f MRS shows high mI/Cr ratio, slightly raised Cho/Cr ratio (1.2) and slightly low NAA/Cr ratio. Focal raised perfusion and choline area was chosen for the optimal site of biopsy