Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 17;11:3598. doi: 10.1038/s41467-020-17325-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a The TAD structure overlaid with gene annotations at the 8q24 region as seen from the HiC data in LNCaP cells. b Plots show 4C on the enhancer viewpoint using 4C-ker pipeline. c 4C plots from PCAT1 promoter viewpoint and d long-range interaction from 4C at PVT1 viewpoint, note the interactions marked by arrows. Tracks below the 4C plots in b–d show the ChIP-seq signal of AR and H3K27ac at the regions. e Comparative HiC in LNCaP and T47D showing the differential interactions at the 8q24 locus in the two cell lines. The red pixels show higher interactions in LNCaP and the blue ones show higher interactions in T47D, the heatmap is overlaid with gene annotations and TADs boundaries. 4C data are provided as source data file.