Fig. 3. Comparison of intracellular and extracellular pyruvate and lactate 13C-label incorporation during 3-h incubation.
a Intracellular pyruvate and lactate 13C-label incorporation. b Peak area count of extracellular pyruvate and lactate. c Extracellular pyruvate and lactate 13C-label incorporation. Monocarboxylate transporter (MCT) mediates bi-directional transport of pyruvate and lactate. Box-plots show the percentage of the intracellular metabolite pool that has accumulated 13C-label.