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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Trends Biotechnol. 2020 Feb 18;38(8):857–872. doi: 10.1016/j.tibtech.2020.01.003

Figure 5. Immunocompetent intestinal MPS models that incorporate differentiated immune subsets.

Figure 5.

(A) An MPS model that induces inflammatory responses in the EMI axis consisting of the intestinal epithelium, endothelium, LPS or bacterial cells, and tissue-resident mucosal macrophages (mMphs) and dendritic cells (DCs). Reproduced from [59] with permission. (B) A NutriChip that assesses the effects of dairy products by reconstituting intestinal epithelium, LPS or dairy food products, and macrophages. Bars, 50 μm. Reproduced from [61] with permission.