Table 3.

Maternal urine cadmium levels at 26 weeks of gestation and child neurodevelopmental test scores at age 1, 2, 3, 4, 5, and 8 years

	Group 1		Group 2		Group 3
	n	Mean ± SD	n	Mean ± SD	n	Mean ± SD
MDI at age 1	118	94.0 ± 9.8	67	93.1 ± 9.4	73	93.9 ±10.6
MDI at age 2	103	90.4 ±13.7	53	86.8 ±15.8	65	89.2 ±14.2
MDI at age 3	92	95.5 ±13.9	49	93.5 ±13.4	59	91.6 ±12.7
FSIQ at age 5	77	105.2 ±14.5	42	98.6 ± 14.5	38	102.2 ±15.5
FSIQ at age 8*	71	106.1 ± 15.9	53	97.1 ± 15.1	49	101.5 ± 15.3
Adaptive Skills score at age 2	103	41.0±6.3	56	41.0±5.8	64	41.7±7.3
Adaptive Skills score at age 3	98	50.8±5.9	51	50.0±7.2	58	50.8±8.2
Adaptive Skills score at age 4	76	49.6±7.1	38	48.6±9.1	38	49.6±9.4
Adaptive Skills score at age 5†	80	52.8±7.7	42	48.2±9.5	41	52.6±8.8
Adaptive Skills score at age 8	76	51.3 ± 8.1	53	47.5 ± 10.5	50	48.7 ± 10.6

Group 1: < LOD; Group 2: 0.06–0.22 μg/g creatinine; Group 3: >0.22 μg/g creatinine.

MDI, Mental Development Index; FSIQ, Full-Scale IQ; AKL, Adaptive Skills score; SD, standard deviation.

^*p<0.05 for FSIQ at age 8 years.

^†p<0.05 for Adaptative Skills score at age 5 years.

The statistical test included analysis of variance.