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. 2020 Jul-Sep;12(3):172–178.

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Copyright© 2020 Avicenna Research Institute

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Effect of hWJMSCs-CM, CM of IGF1-hWJMSCs toward IL10 level on OA cells model. (I) Normal cell (CHON002), (II) IL-1β-CHON002, (III) hWJMSCs-CM 15%+IL1β- CHON002 (IV), hWJMSCs-CM 30%+IL1β-CHON002, (V) IGF1-hWJMSCs-CM 15%+IL1β-CHON002, (VI) IGF1-hWJMSCs-CM 30%+IL1β-CHON002. The histograms are presented as mean±standard deviation, the treatment was done triplicate. The data were analyzed with ANOVA and Tukey post hoc test. Different letters (a, b, c) indicate significant differences in 1 week incubation (Blue color) and different letters (A, B, C, D) indicate significant differences in 2 week incubation (Gray color). The symbol (*) presents significant differences between week 1 and week 2 based on paired t-test (p<0.05).