Table 3.
The specificity and sensitivity of flow cytometry methods
| Flow cytometry by Anti-CK19 | Immunomagnetic flow cytometry (MACS) CK7, CK8, CK18, CK19, EpCAM (Pan marker) | Total number | p | |
|---|---|---|---|---|
| Healthy control | 0 | 0 | 35 (100%) | - |
| Stage I patients | 0 | 0 | 4 | - |
| Stage II patients | 12 (54.5%) | 6 (27.2%) | 22 | - |
| Stage III patients | 5 (83.3%) | 6 (100%) | 6 | - |
| Stage IV patients | 2 (100%) | 2 (100%) | 2 | - |
| Not defined | 1 (100%) | 0 | 1 | - |
| Total patients | 20 (57.1%) | 14 (40%) | 35 (100%) | - |
| Specificity | 100% | 100% | 100% | 0.085* |
| Sensitivity | 57.1% | 40% | 97.1% | 0.318 |
| p-value at different stages | 0.037* | 0.001* | - | - |
*
Statistically significant p-value.