Table 4.
Baseline patient‐reported outcome measures in patients with axSpA at enrollment, stratified by enthesitis status
| Characteristic | Patients with axSpAa | P valueb | |
|---|---|---|---|
| With enthesitis (n = 121) | No enthesitis (n = 356) | ||
| Patient pain (VAS 0‐100) | 57.5 (26.7) | 43.5 (29.5) | <0.01 |
| Patient fatigue (VAS 0‐100) | 56.5 (27.5) | 45.0 (28.6) | <0.01 |
| Patient global assessment (VAS 0‐100) | 49.8 (29.7) | 54.1 (32.9) | 0.56 |
| HAQ‐DI (0‐3) | 0.9 (0.7) | 0.6 (0.6) | <0.01 |
| HAQ‐S (0‐3) | 0.9 (0.7) | 0.6 (0.6) | <0.01 |
| EQ‐5D (0‐1) | 0.7 (0.2) | 0.7 (0.2) | <0.01 |
| EQ (VAS 0‐100): patient health today | 59.7 (22.7) | 66.4 (22.0) | <0.01 |
| WPAI‐GH domains | |||
| % Work time missed | 9.0 (18.8) | 5.8 (16.8) | 0.06 |
| % Impairment while working | 38.3 (27.4) | 25.3 (24.4) | <0.01 |
| % Overall work impairment | 41.4 (29) | 27.6 (26.6) | <0.01 |
| % Activity impairment | 49.8 (29.5) | 35.6 (29.3) | <0.01 |
| Current employment, n (%) | 75 (63.0) | 241 (68.7) | 0.26 |
| Morning stiffness, n (%) | n = 117 | n = 318 | 0.72 |
| <30 min | 28 (23.9) | 71 (22.3) | |
| ≥30 min | 89 (76.1) | 247 (77.7) | |
Abbreviation: axSpA, axial spondyloarthritis; EQ‐5D, EuroQol 5‐dimension questionnaire; HAQ‐DI, Health Assessment Questionnaire Disability Index; HAQ‐S, Health Assessment Questionnaire for the Spondyloarthropathies; VAS, visual analog scale; WPAI‐GH, Work Productivity and Activity Impairment Questionnaire‐General Health.
All values were calculated based on available data and are presented as mean (SD) unless otherwise stated and had less than 20% missing data except for patient global assessment, HAQ‐DI, HAQ‐S, and WPAI‐GH1 to WPAI‐GH3.
P value for comparison between patients with versus those without enthesitis. The Wilcoxon rank‐sum test was used for disease activity measurements, whereas the χ2 test was used for categorical variables.