Table 3.
ORs for reporting medication efficacy, cost, or characteristics as the most important factor in the decision‐making process (N = 397) a
| Variable | Most Important Medication Attribute | |||||
|---|---|---|---|---|---|---|
| Efficacy | Cost | Medication Characteristics b | ||||
| n (%) c | OR (95% CI) d | n (%) c | OR (95% CI) d | n (%) c | OR (95% CI) d | |
| Age, y | … | 0.99 (0.97‐1.01) | … | 1.02 (0.99‐1.04) | … | 0.99 (0.96‐1.02) |
| Sex | ||||||
| Male | 90 (45.9) | Reference | 71 (36.2) | Reference | 32 (16.3) | Reference |
| Female | 87 (43.3) | 1.11 (0.70‐1.75) | 81 (40.3) | 0.99 (0.62‐1.56) | 24 (11.9) | 0.66 (0.35‐1.25) |
| Race/ethnicity | ||||||
| Non‐Hispanic white | 136 (43.5) | Reference | 130 (41.5) | Reference | 37 (11.8) | Reference |
| Non‐Hispanic black, Latino, non‐Hispanic Asian, or other | 41 (48.8) | 1.12 (0.63‐1.97) | 22 (26.2) | 0.58 (0.32‐1.06) | 19 (22.6) | 1.96 (0.96‐4.00) |
| Education | ||||||
| High school or less | 16 (37.2) | Reference | 17 (39.5) | Reference | 9 (20.9) | Reference |
| Some college | 34 (43.0) | 1.13 (0.49‐2.56) | 32 (40.5) | 1.05 (0.46‐2.39) | 11 (13.9) | 0.75 (0.26‐2.16) |
| College degree | 53 (39.0) | 0.78 (0.35‐1.73) | 63 (46.3) | 1.66 (0.75‐3.66) | 16 (11.8) | 0.59 (0.21‐1.61) |
| Graduate degree | 74 (53.2) | 1.11 (0.49‐2.52) | 40 (28.8) | 0.90 (0.39‐2.08) | 20 (14.4) | 0.84 (0.29‐2.37) |
| Relationship status | ||||||
| Married or long‐term relationship | 130 (44.1) | Reference | 113 (38.3) | Reference | 44 (14.9) | Reference |
| Not married | 47 (46.1) | 1.26 (0.73‐2.20) | 39 (38.2) | 0.85 (0.48‐1.51) | 12 (11.8) | 0.81 (0.37‐1.80) |
| Employment status | ||||||
| Unemployed | 56 (44.4) | Reference | 48 (38.1) | Reference | 18 (14.3) | Reference |
| Employed or student | 121 (44.7) | 0.83 (0.47‐1.47) | 104 (38.4) | 1.56 (0.86‐2.82) | 38 (14.0) | 0.59 (0.26‐1.32) |
| Total household income | ||||||
| ≤$50 000 | 33 (37.5) | Reference | 41 (46.6) | reference | 13 (14.8) | Reference |
| $50 001‐$100 000 | 37 (37.4) | 0.95 (0.48‐1.88) | 45 (45.5) | 1.03 (0.52‐2.02) | 13 (13.1) | 0.73 (0.28‐1.89) |
| $100 001‐$200 000 | 43 (35.0) | 0.97 (0.47‐1.99) | 51 (41.5) | 0.75 (0.36‐1.55) | 25 (20.3) | 1.28 (0.49‐3.33) |
| ≥$200 001 | 44 (78.6) | 6.38 (2.51‐16.22) | 10 (17.9) | 0.27 (0.10‐0.71) | 2 (3.6) | 0.14 (0.03‐0.76) |
| Prefer not to say | 20 (64.5) | 2.72 (1.08‐6.87) | 5 (16.1) | 0.26 (0.09‐0.80) | 3 (9.7) | 0.45 (0.11‐1.94) |
| Physical activity vs. others | ||||||
| Much less active | 15 (26.8) | Reference | 34 (60.7) | Reference | 4 (7.1) | Reference |
| Less active | 33 (41.8) | 2.15 (0.95‐4.88) | 30 (38.0) | 0.39 (0.18‐0.84) | 11 (13.9) | 1.81 (0.51‐6.49) |
| Similar | 53 (49.5) | 2.70 (1.22‐5.96) | 38 (35.5) | 0.38 (0.18‐0.80) | 15 (14.0) | 2.11 (0.61‐7.25) |
| More active | 50 (52.6) | 2.39 (1.04‐5.52) | 30 (31.6) | 0.40 (0.18‐0.89) | 14 (14.7) | 2.45 (0.68‐8.78) |
| Much more active | 26 (43.3) | 1.47 (0.59‐3.62) | 20 (33.3) | 0.51 (0.22‐1.21) | 12 (20.0) | 3.37 (0.89‐12.79) |
| Duration of axSpA symptoms, y | … | 1.030 (1.009‐1.052) | … | 0.978 (0.957‐0.999) | … | 0.988 (0.958‐1.018) |
| BASDAI score | … | 0.99 (0.88‐1.10) | … | 1.07 (0.95‐1.20) | … | 0.94 (0.81‐1.10) |
| Biologic medication use | ||||||
| Biologic naïve | 46 (38.7) | Reference | 51 (42.9) | Reference | 17 (14.3) | Reference |
| Prior use of biologics | 17 (38.7) | 1.04 (0.48‐2.27) | 22 (50.0) | 1.34 (0.62‐2.89) | 5 (11.4) | 0.73 (0.23‐2.32) |
| Currently using biologics | 114 (48.7) | 1.49 (0.87‐2.56) | 79 (33.8) | 0.71 (0.41‐1.23) | 34 (14.5) | 0.94 (0.44‐1.97) |
Abbreviation: axSpA, axial spondyloarthritis; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; CI, confidence interval; OR, odds ratio.
We did not conduct a regression on reporting of the side effect profile as the most important factor in the decision‐making process because only 12 individuals prioritized it in the study.
Includes route of administration, dosing frequency, and clinic visit and laboratory test frequency.
Represents the number of persons prioritizing the respective factor as the most important in their decision‐making process.
The multivariable logistic regression model included all covariates in the table. Insurance status was not included in the model because 97.5% of respondents had health insurance.