Table 3.
Risk and Risk Difference of the Metabolic Risk Factors in Patients with Psoriasis Compared to Individuals Without Psoriasis in Six Months, One Year, Five Years and 10 Years After Dispensing Date
| Non Psoriasis | Psoriasis | Difference | ||||
|---|---|---|---|---|---|---|
| Risk | 95% CI | Risk | 95% CI | Risk | 95% CI | |
| Hypertension | ||||||
| Mild | ||||||
| Predicted risk at 6m | 0.15 | 0.15–0.15 | 0.17 | 0.17–0.18 | 0.02 | 0.02–0.03 |
| Predicted risk at 1y | 0.18 | 0.18–0.18 | 0.22 | 0.21–0.22 | 0.04 | 0.03–0.04 |
| Predicted risk at 5y | 0.35 | 0.35–0.35 | 0.41 | 0.41–0.42 | 0.07 | 0.06–0.07 |
| Predicted risk at 10y | 0.50 | 0.50–0.50 | 0.57 | 0.57–0.58 | 0.07 | 0.07–0.08 |
| Moderate | ||||||
| Predicted risk at 6m | 0.16 | 0.15–0.16 | 0.18 | 0.18–0.19 | 0.03 | 0.02–0.03 |
| Predicted risk at 1y | 0.19 | 0.19–0.19 | 0.23 | 0.22–0.23 | 0.04 | 0.03–0.05 |
| Predicted risk at 5y | 0.36 | 0.35–0.36 | 0.44 | 0.43–0.44 | 0.08 | 0.07–0.09 |
| Predicted risk at 10y | 0.52 | 0.51–0.52 | 0.61 | 0.60–0.61 | 0.09 | 0.08–0.10 |
| Severe | ||||||
| Predicted risk at 6m | 0.11 | 0.11–0.12 | 0.15 | 0.14–0.17 | 0.04 | 0.03–0.05 |
| Predicted risk at 1y | 0.14 | 0.13–0.14 | 0.20 | 0.19–0.21 | 0.06 | 0.05–0.07 |
| Predicted risk at 5y | 0.27 | 0.27–0.28 | 0.40 | 0.39–0.41 | 0.13 | 0.12–0.14 |
| Predicted risk at 10y | 0.42 | 0.41–0.43 | 0.58 | 0.56–0.59 | 0.16 | 0.14–0.17 |
| Hypercholesterolemia | ||||||
| Mild | ||||||
| Predicted risk at 6m | 0.12 | 0.12–0.12 | 0.15 | 0.14–0.15 | 0.03 | 0.03–0.04 |
| Predicted risk at 1y | 0.13 | 0.13–0.14 | 0.17 | 0.17–0.18 | 0.04 | 0.04–0.04 |
| Predicted risk at 5y | 0.21 | 0.21–0.21 | 0.27 | 0.27–0.27 | 0.06 | 0.05–0.06 |
| Predicted risk at 10y | 0.29 | 0.29–0.29 | 0.36 | 0.35–0.37 | 0.07 | 0.06–0.07 |
| Moderate | ||||||
| Predicted risk at 6m | 0.12 | 0.12–0.12 | 0.14 | 0.14–0.15 | 0.02 | 0.02–0.03 |
| Predicted risk at 1y | 0.14 | 0.13–0.14 | 0.17 | 0.16–0.17 | 0.03 | 0.03–0.04 |
| Predicted risk at 5y | 0.22 | 0.21–0.22 | 0.27 | 0.27–0.28 | 0.06 | 0.05–0.06 |
| Predicted risk at 10y | 0.30 | 0.30–0.30 | 0.37 | 0.36–0.38 | 0.07 | 0.06–0.08 |
| Severe | ||||||
| Predicted risk at 6m | 0.08 | 0.08–0.09 | 0.10 | 0.09–0.11 | 0.02 | 0.01–0.03 |
| Predicted risk at 1y | 0.10 | 0.09–0.10 | 0.12 | 0.11–0.13 | 0.03 | 0.02–0.04 |
| Predicted risk at 5y | 0.16 | 0.15–0.16 | 0.22 | 0.21–0.24 | 0.07 | 0.06–0.08 |
| Predicted risk at 10y | 0.23 | 0.22–0.23 | 0.33 | 0.32–0.35 | 0.10 | 0.09–0.12 |
| Diabetes | ||||||
| Mild | ||||||
| Predicted risk at 6m | 0.03 | 0.03–0.03 | 0.04 | 0.04–0.05 | 0.02 | 0.01–0.02 |
| Predicted risk at 1y | 0.04 | 0.04–0.04 | 0.06 | 0.06–0.06 | 0.02 | 0.02–0.03 |
| Predicted risk at 5y | 0.08 | 0.08–0.08 | 0.13 | 0.13–0.14 | 0.05 | 0.05–0.05 |
| Predicted risk at 10y | 0.13 | 0.13–0.13 | 0.19 | 0.18–0.19 | 0.06 | 0.06–0.07 |
| Moderate | ||||||
| Predicted risk at 6m | 0.03 | 0.03–0.03 | 0.05 | 0.04–0.05 | 0.02 | 0.01–0.02 |
| Predicted risk at 1y | 0.04 | 0.04–0.04 | 0.06 | 0.06–0.07 | 0.02 | 0.02–0.03 |
| Predicted risk at 5y | 0.08 | 0.08–0.09 | 0.14 | 0.13–0.14 | 0.05 | 0.05–0.06 |
| Predicted risk at 10y | 0.13 | 0.13–0.13 | 0.20 | 0.2–0.21 | 0.07 | 0.06–0.08 |
| Severe | ||||||
| Predicted risk at 6m | 0.02 | 0.02–0.02 | 0.04 | 0.04–0.05 | 0.02 | 0.01–0.03 |
| Predicted risk at 1y | 0.03 | 0.03–0.03 | 0.06 | 0.05–0.07 | 0.03 | 0.02–0.04 |
| Predicted risk at 5y | 0.06 | 0.06–0.07 | 0.14 | 0.13–0.15 | 0.07 | 0.06–0.09 |
| Predicted risk at 10y | 0.11 | 0.10–0.11 | 0.21 | 0.20–0.23 | 0.11 | 0.09–0.12 |
Abbreviations: m, month; y, year.