Figure 2.

Alterations in blood chemistry in NiV-infected hamsters euthanized with respiratory or neurological disease and in survivors. Age-matched female Syrian hamsters were mock-infected (Dulbecco’s days post infection modified Eagle’s medium only, circles; n = 13 for Metlac 12 analytes or n = 19 for General Chemistry 13 analytes) or infected with NiV-Malaysia and followed for up to 28 days post infection. Samples collected at euthanasia were analyzed using the Piccolo General Chemistry 13 (plasma) or Metlac 12 (whole blood) reagent discs. NiV-infected hamsters were grouped based on clinical presentation at time of euthanasia (respiratory [n = 21, inverted triangles] or neurological [n = 36, triangles]) or as survivors (n = 34, diamonds). Subjects with both respiratory and neurological signs were excluded from analyses (n = 5). Individual values and median (red bar) are depicted. *, P < .01; **, P < .001; ***, P < .0001. ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AMY, amylase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; Ca, total calcium; Cl⁻, chloride; CRE, creatinine; GLU, blood glucose; K⁺, potassium; LAC, lactate; Mg, magnesium; Na⁺, sodium; PHOS, phosphorus; tCO₂, total carbon dioxide; TP, total protein.