Table 2.
Prevalence of hypertension-mediated organ damage by self-reported hypertension onset age
| Self-reported HTN onset age | ||||||
|---|---|---|---|---|---|---|
| All | <35 y | 35–44 y | ≥45 y | No HTN | P value | |
| N | 2,649 | 194 | 297 | 340 | 1,818 | |
| LVMI, g/m2 (SD) | 85 (21.3) | 94 (25.6) | 91 (25.1) | 90 (21.4) | 82 (19.4) | <0.001 |
| LVH, n (%) | 437 (16.5) | 66 (34.0) | 65 (21.9) | 75 (22.1) | 231 (12.7) | <0.001 |
| E/A ratio (SD) | 1.3 (0.4) | 1.17 (0.3) | 1.24 (0.4) | 1.20 (0.3) | 1.35 (0.4) | <0.001 |
| LVDD, n (%) | 234 (8.8) | 29 (15.0) | 27 (9.1) | 40 (11.8) | 138 (7.6) | 0.001 |
| CAC-score, AU (SD) | 40 (206) | 140 (542) | 60 (288) | 57 (168) | 23 (103) | <0.001 |
| Coronary calcification, n (%) | 230 (8.7) | 40 (20.6) | 34 (11.5) | 49 (14.4) | 107 (5.9) | <0.001 |
| UACR, median (Q1–Q3) | 4.8 (3.3–8.4) | 6.6 (4.0–16.5) | 6.2 (4.0–12.9) | 5.4 (3.6–9.7) | 4.4 (3.1–7.2) | <0.001 |
| Albuminuria, n (%) | 159 (6.0) | 26 (13.4) | 38 (12.8) | 28 (8.2) | 67 (3.7) | <0.001 |
Abbreviations: AU, Agatston units; CAC-score, coronary artery calcification score; E/A ratio, ratio between E wave peak velocity flow in early diastole and A wave peak velocity flow in late diastole; HTN, hypertension; LVDD, left ventricular diastolic dysfunction; LVH, left ventricular hypertrophy; LVMI, left ventricular mass index; Q1, lower quartile; Q3, upper quartile; SD, standard deviation; UACR, urine albumin/creatinine ratio.