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. 2019 Nov 5;221(Suppl 4):S419–S430. doi: 10.1093/infdis/jiz502

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Published by Oxford University Press for the Infectious Diseases Society of America 2019.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 2. — (A), A small focal lesion (arrows) appeared on day 15 after exposure in the left frontal subcortical white matter in 1 animal (8078). (B), Progression of disease is noted on day 17 (terminal day), with a total of 7 abnormal signal intensities now seen bilaterally. Incidental note is made of a preexisting congenital abnormality in this animal (colpocephaly, dilatation of the left posterior occipital horn). Abbreviations: DW, diffusion weighted; FLAIR, fluid-attenuated inversion-recovery; trace (DT), trace of diffusion tensor.