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Effects of PI3K inhibitor LY294002 on the viability of PC12 cells (×100). The PC12 cells were pretreated with LY294002 (20 μM) or not for 1 hour; then cells were treated with HAS (60 μM) for 2 h, subsequently subjected to H2O2 (90 μM) for 4 h. HAS: hydroxy-α-sanshool; Norm.: normal. The values were represented as the mean ± SD (n = 3). ∗∗P < 0.01 vs. the control group.
