Table 3.
The use of various antiepileptic drugs in the sample population.
| Variables | Number of participants (n = 153) | Children with uncontrolled seizure (n = 108) | Children with AED related adverse effects (n = 13) | Children with unrelated systemic adverse effects (n = 24) |
|---|---|---|---|---|
| Number of AEDs (mean, SD) | 1.93 ± 0.82 | 2.32 ± 0.71 | 2.86 ± 0.89 | 2.01 ± 0.87 |
| Number of patients on 1 AED | 105(68 %) | 67(62 %) | 0 | 16 (67 %) |
| Number of patients on 2 AEDs | 32(21 %) | 27(25 %) | 6(46 %) | 4(16 %) |
| Number of patients on 3 AEDs | 13(8.4 %) | 11(10 %) | 5(38 %) | 3(12 %) |
| Number of patients on 4 AEDs | 3(2 %) | 3(2.7 %) | 2(15 %) | 1(4 %) |
| Phenytoin | 37(24 %) | 29(26.8 %) | 11(84 %) | 8(33 %) |
| Valproate | 72(47 %) | 58(53.7 %) | 2(15 %) | 12(50 %) |
| Levetiracetam | 51(33 %) | 37(34.2 %) | 0 | 9(37 %) |
| Benzodiazepine | 25(16.3 %) | 16(14.8 %) | 12(92 %) | 2(8 %) |
| Oxcarbazepine | 20(13 %) | 13(12 %) | 9(69 %) | 4(16 %) |
| Topiramate | 6(4 %) | 5(4.6 %) | 1(7.6 %) | 1(4 %) |
| Zonisamide | 3(2 %) | 3(2.7 %) | 0 | 1(4 %) |
| Lamotrigine | 4(2.6 %) | 3(2.7 %) | 0 | 0 |
| Lacosamide | 2(1.3 %) | 2(1.8 %) | 0 | 0 |