Table 3.
A. Experiment-1: SCZ (n=38) versus HC (n=20) | ||||||||
---|---|---|---|---|---|---|---|---|
10-fold method | SVM Model | Hold-out method | ||||||
ACC (%) | SEN (%) | SPE (%) | AUC (%) | ACC (%) | SEN (%) | SPE (%) | AUC (%) | |
72.41 | 86.84 | 45.00 | 65.92 | Linear SVM | 73.68 | 92.31 | 33.33 | 62.82 |
70.69 | 78.95 | 55.00 | 66.97 | Quadratic SVM | 78.95†† | 92.31 | 50.00 | 71.15 |
63.79 | 68.42 | 55.00 | 61.71 | Cubic SVM | 68.42 | 76.92 | 50.00 | 63.46 |
70.69 | 97.37 | 20.00 | 58.68 | Fine Gaussian SVM | 68.42 | 100.00 | 0.00 | 50.00 |
63.79 | 92.11 | 10.00 | 51.05 | Medium Gaussian SVM | 73.68 | 100.00 | 16.67 | 58.33 |
65.52 | 97.37 | 5.00 | 51.18 | Coarse Gaussian SVM | 68.42 | 100.00 | 0.00 | 50.00 |
B. Experiment-2: PS (n=18) versus NS (n=10) | ||||||||
10-fold method | SVM Model | Hold-out method | ||||||
ACC (%) | SEN (%) | SPE (%) | AUC (%) | ACC (%) | SEN (%) | SPE (%) | AUC (%) | |
85.71 | 88.89 | 80.00 | 84.44 | Linear SVM | 88.89 | 100.00 | 75.00 | 87.50 |
82.14 | 83.33 | 80.00 | 81.67 | QUADRATIC SVM | 88.89 | 100.00 | 75.00 | 87.50 |
82.14 | 83.33 | 80.00 | 81.67 | Cubic SVM | 88.89 | 100.00 | 75.00 | 87.50 |
64.29 | 100.00 | 0.00 | 50.00 | Fine Gaussian SVM | 55.56 | 100.00 | 0.00 | 50.00 |
89.29†† | 100.00 | 70.00 | 85.00 | Medium Gaussian SVM | 77.78 | 100.00 | 50.00 | 75.00 |
64.29 | 100.00 | 0.00 | 50.00 | Coarse Gaussian SVM | 55.56 | 100.00 | 0.00 | 50.00 |
†† Model showing highest accuracy. SVM – Support vector machine; ACC – Accuracy; SEN – Sensitivity; SPE – Specificity; AUC – Area under receiver operating curve; SCZ –Schizophrenia patients; HC – Healthy controls; PS – Schizophrenia patients with predominant positive symptoms; NS – Schizophrenia patients with predominant negative symptoms