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Trajectory modeling identified multiple distinct trajectory groups with 95% CIs (between dashed lines) for PRO (A), LDL-C (B), SBP (C), UA (D), HbA1c (E). The ESKD risks were compared according to trajectory groups of those key clinical parameters with fully adjusted HRs (low-stable trajectory as reference) (F). ESKD, end-stage kidney disease; HbA1c, hemoglobin A1c; LDL-C, low-density lipoprotein cholesterol; PRO, proteinuria; SBP, systolic blood pressure; UA, uric acid.
