Table 3.
The Univariate and Multivariate Analysis of OS in Glioma Patients
| Variables | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Sex | ||||
| Male | Reference | 0.277 | Reference | 0.296 |
| Female | 0.806 (0.546–1.190) | 0.804 (0.534–1.211) | ||
| Age (y) | ||||
| <50 | Reference | <0.001 | Reference | <0.001 |
| ≥50 | 4.356 (2.826–6.714) | 4.296 (2.748–6.716) | ||
| Tumor size (cm) | ||||
| <5 | Reference | 0.005 | Reference | 0.702 |
| ≥5 | 1.748 (1.181–2.588) | 0.922 (0.609–1.396) | ||
| WHO Grade | ||||
| I + II | Reference | <0.001 | Reference | <0.001 |
| III + IV | 6.175 (4.070–9.367) | 5.951 (3.694–9.588) | ||
| KPS | ||||
| <70 | Reference | 0.003 | Reference | <0.001 |
| ≥70 | 0.544 (0.364–0.814) | 0.436 (0.281–0.675) | ||
| Radiotherapy/Chemotherapy | ||||
| Yes | Reference | 0.994 | Reference | 0.885 |
| No | 1.001 (0.669–1.499) | 1.031 (0.683–1.557) | ||
| ENS | ||||
| Score=0 | Reference | <0.001 | Reference | 0.047 |
| Score=1 | 1.902 (1.064–3.400) | 0.030 | 1.572 (0.870–2.841) | 0.134 |
| Score=2 | 3.843 (2.175–6.791) | <0.001 | 2.152 (1.163–3.983) | 0.015 |
Abbreviations: KPS, Karnofsky performance status; ENS, the combination of eosinophils, and neutrophil to lymphocyte ratio; HR, hazard ratio; CI, confidence interval.