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. 2020 Jul 14;13:6897–6905. doi: 10.2147/OTT.S245578

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© 2020 Luo et al.

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PIM3 overexpression promotes acute myeloid leukemia (AML) cell proliferation and survival. (A) Growth of control (CTR-OE) and PIM3-overexpressing (Pim3-OE) K562 AML cells. (B) Growth of control (U937-CTR) and PIM3-overexpressing (U937-Pim3) U937 AML cells. (C) The apoptotic cells were detected by staining with annexin V and PI and flow cytometry. The results are quantified in (D). *p < 0.05, **p < 0.01, ***p < 0.001.