Table 3.
VIP Variants Within the Pharmacogenes in Chechen Compared to HapMap Populations
SNP ID | Populations | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CHE | ASW | CEU | CHB | CDX | GBR | GIH | JPT | LWK | MXL | TSI | YRI | ACB | |
rs3918290 | 0.003a | 0.008a | 0.005a | 0.00a | 0.00a | 0.00a | 0.146a | 0.00a | 0.00a | 0.00a | 0.005a | 0.00a | 0.00a |
0.54b | 0.13b | 0.62b | 0.56b | 0.55b | 2.3b | 0.63b | 0.60b | 0.39b | 0.09b | 0.65b | 0.57b | ||
0.46c | 0.71c | 0.43c | 0.45c | 0.45c | 0.13c | 0.43c | 0.44c | 0.53c | 0.75c | 0.42c | 0.45c | ||
rs689466 | 0.11a | 0.13a | 0.19a | 0.47a | 0.52a | 0.20a | 0.13a | 0.44a | 0.03a | 0.26a | 0.20a | 0.07a | 0.10a |
0.34b | 6.6b | N/Ab | N/Ab | 7.2b | 0.26b | N/Ab | 10.9b | 15.3b | 7.5b | 2.1b | 0.1b | ||
0.56c | 0.01c | N/Ac | N/Ac | 0.01c | 0.60c | N/Ac | 1e-3c | 1e-4c | 0.01c | 0.14c | 0.79c | ||
rs1805124 | 0.25a | 0.26a | 0.18a | 0.12a | 0.07a | 0.22a | 0.20a | 0.13a | 0.30a | 0.16a | 0.23a | 0.32a | 0.28a |
0.04b | 3.5b | 12.5b | 26.2b | 0.49b | 1.7b | 10.9b | 1.6b | 4.1b | 0.26b | 3.7b | 0.5b | ||
0.84c | 0.06c | 4e-4c | 3e-7c | 0.48c | 0.19c | 1e-3c | 0.21c | 0.04c | 0.61c | 0.05c | 0.47c | ||
rs3814055 | 0.33a | 0.29a | 0.34a | 0.27a | 0.15a | 0.40a | 0.42a | 0.25a | 0.30a | 0.33a | 0.36a | 0.27a | 0.39a |
0.62b | 0.01b | 2.3b | 19.2b | 33.2b | 3.8b | 3.8b | 0.55b | 0.001b | 0.37b | 2.2b | 2.0b | ||
0.42c | 0.92c | 0.12c | 1e-5c | 1e-8c | 0.05c | 0.05c | 0.45c | 0.97c | 0.54c | 0.13c | 0.15c | ||
rs1065776 | 0.01a | 0.20a | 0.05a | 0.03a | 0.02a | 0.02a | 0.10a | 0.07a | 0.21a | 0.05a | 0.03a | 0.22a | 0.20a |
N/Ab | 10.43b | 4.3b | 0.52b | 1.4b | 25.7b | 15.7b | N/Ab | 6.9b | 4.1b | N/Ab | N/Ab | ||
N/Ac | 0.001c | 0.04c | 0.46c | 0.22c | 3.9e-7c | 7e-5c | N/Ac | 0.01c | 0.04c | N/Ac | N/Ac | ||
rs701265 | 0.17a | 0.67a | 0.17a | 0.28a | 0.19a | 0.13a | 0.21a | 0.27a | 0.80a | 0.20a | 0.16a | 0.81a | 0.72a |
N/Ab | 0.001b | 11.1b | 0.42b | 1.0b | 1.6b | 9.1b | N/Ab | 0.89b | 0.004b | N/Ab | N/Ab | ||
N/Ac | 0.97c | 0.001c | 0.51c | 0.31c | 0.21c | 0.002c | N/Ac | 0.34c | 0.95c | N/Ac | N/Ac | ||
rs975833 | 0.24a | 0.25a | 0.24a | 0.79a | 0.75a | 0.24a | 0.49a | 0.80a | 0.19a | 0.13a | 0.27a | 0.30a | 0.28a |
0.08b | 0.001b | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | 1.7b | 6.5b | 0.6b | 2.4b | 0.79b | ||
0.77c | 0.97c | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | 0.19c | 0.01c | 0.43c | 0.12c | 0.37c | ||
rs2066702 | 0.01a | 0.20a | 0.00a | 0.00a | 0.00a | 0.00a | 0.00a | 0.00a | 0.14a | 0.03a | 0.00a | 0.28a | 0.19a |
N/Ab | 2.4b | 2.5b | 2.3b | 2.2b | 2.5b | 2.5b | N/Ab | 1.9b | 2.6b | N/Ab | N/Ab | ||
N/Ac | 0.12c | 0.11c | 0.13c | 0.14c | 0.11c | 0.11c | N/Ac | 0.16c | 0.11c | N/Ac | N/Ac | ||
rs1229984 | 0.12a | 0.00a | 0.02a | 0.71a | 0.63a | 0.01a | 0.02a | 0.73a | 0.00a | 0.08a | 0.05a | 0.00a | 0.01a |
16.5b 5e-5c |
19.1b 1e-5c |
N/Ab N/Ac |
N/Ab N/Ac |
21.8b 3e-6c |
16.0b 6e-5c |
N/Ab N/Ac |
26.5b 2.6e-7c |
1.3b 0.25c |
7.8b 0.005c |
28.8b 8e-8c |
20.6b 6e-6c |
||
rs698 | 0.27a | 0.14a | 0.47a | 0.05a | 0.11a | 0.44a | 0.28a | 0.07a | 0.14a | 0.28a | 0.31a | 0.07a | 0.11a |
8.1b | 23.7b | N/Ab | 16.9b | 15.9b | 0.14b | 31.2b | 11.3b | 0.10b | 1.1b | 33.1b | 18.1b | ||
0.004c | 1e-6c | N/Ac | 4e-5c | 7e-5c | 0.71c | 2e-8c | 0.001c | 0.75c | 0.29c | 1e-8c | 2e-5c | ||
rs17244841 | 0.03a | 0.10a | 0.01a | 0.00a | 0.00a | 0.03a | 0.00a | 0.02a | 0.08a | 0.04a | 0.03a | 0.09a | 0.10a |
9.8b | 0.87b | 5.8b | 5.2b | N/Ab | 5.2b | 0.39b | 8.7b | 0.38b | 0.11b | 10.7b | 13.3b | ||
0.002c | 0.35c | 0.02 | 0.02c | N/Ac | 0.02c | 0.53c | 0.003c | 0.53c | 0.74c | 0.001c | 3e-4c | ||
rs3846662 | 0.43a | 0.13a | 0.57a | 0.48 | 0.49a | 0.55a | 0.34a | 0.47a | 0.03a | 0.56a | 0.57a | 0.04a | 0.11a |
N/Ab | 0.04b | 3.3b | 2.5b | 0.14b | 26.1b | 7.1b | N/Ab | 0.005b | 0.008b | N/Ab | N/Ab | ||
N/Ac | 0.83c | 0.06c | 0.12c | 0.17c | 3.2e-7c | 0.008c | N/Ac | 0.94c | 0.93c | N/Ac | N/Ac | ||
rs17238540 | 0.03a | 0.10a | 0.01a | 0.00a | 0.00a | 0.02a | 0.00a | 0.00a | 0.09a | 0.04a | 0.03a | 0.10a | 0.09a |
7.9b | 1.5b | 6.9b | 6.3b | 0.5b | 6.9b | 7.0b | 8.0b | 0.09b | 0.001b | 9.7b | 8.5b | ||
0.005c | 0.21c | 0.008c | 0.01c | 0.47c | 0.008c | 0.008c | 0.004c | 0.76c | 0.97c | 0.002c | 0.003c | ||
rs1042713 | 0.37a | 0.54a | 0.35a | 0.55a | 0.58a | 0.42a | 0.43a | 0.44a | 0.49a | 0.48a | 0.37a | 0.53a | 0.51a |
11.3a | 0.33b | 15.8b | 20.7b | 0.96b | 1.8b | 2.5b | 7.0b | 4.1b | 0.01b | 13.4b | 9.3b | ||
0.001c | 0.56c | 7e-5c | 5e-6c | 0.32 | 0.18c | 0.11c | 0.008c | 0.04c | 0.92c | 0.0002c | 0.002c | ||
rs1042714 | 0.31a | 0.12a | 0.46a | 0.11a | 0.10a | 0.39a | 0.23a | 0.06a | 0.21a | 0.14a | 0.14a | 0.12a | 0.16a |
16.7b | 12.1b | 30.2b | 29.3b | 3.5b | 4.6b | N/Ab | 6.3b | 14.1b | 3.6b | 27.0b | 14.6b | ||
4e-5c | 5e-4c | 4e-8c | 6e-8c | 0.06c | 0.03c | N/Ac | 0.01c | 2e-4c | 0.06c | 2.1e-7c | 1e-4c | ||
rs1800888 | 0.003a | 0.00a | 0.02a | 0.00a | 0.00a | 0.02a | 0.00a | 0.00a | 0.00a | 0.00a | 0.01a | 0.00a | 0.00a |
0.36b | 2.4b | 0.62b | 0.56b | 4.3b | 0.62b | 0.62b | 0.59b | 0.38b | 2.2b | 0.65b | 0.57b | ||
0.54c | 0.11c | 0.43c | 0.45c | 0.04c | 0.43c | 0.42c | 0.44c | 0.53c | 0.14c | 0.42c | 0.45c | ||
rs2066853 | 0.13a | 0.34a | 0.09a | 0.37a | 0.26a | 0.09a | 0.12a | 0.46a | 0.48a | 0.13a | 0.09a | 0.45a | 0.47a |
28.0b | 1.5b | N/Ab | 14.4b | 0.87b | 0.11b | N/Ab | N/Ab | 0.03b | 1.02b | N/Ab | N/Ab | ||
1.2e-7c | 0.21c | N/Ac | 2e-4c | 0.35c | 0.73c | N/Ac | N/Ac | 0.85c | 0.31c | N/Ac | N/Ac | ||
rs3815459 | 0.27a | 0.42a | 0.20a | 0.71a | 0.56a | 0.15a | 0.35a | 0.80a | 0.39a | 0.39a | 0.23a | 0.33a | 0.31a |
9.5b | 3.2b | N/Ab | 6.6b | 8.5b | 3.2b | N/Ab | 8.6b | 7.6b | 0.74b | 2.8b | 1.5b | ||
0.002c | 0.07c | N/Ac | 0.01c | 0.003c | 0.07c | N/Ac | 0.003c | 0.006c | 0.39c | 0.09c | 0.22c | ||
rs3807375 | 0.63a | 0.27a | 0.65a | 0.25a | 0.26a | 0.70a | 0.61a | 0.20a | 0.20a | 0.43a | 0.66a | 0.23a | 0.26a |
N/Ab | 0.33b | N/Ab | N/Ab | 3.1b | 1.0b | N/Ab | N/Ab | N/Ab | 0.59b | N/Ab | N/Ab | ||
N/Ac | 0.56c | N/Ac | N/Ac | 0.08c | 0.31c | N/Ac | N/Ac | N/Ac | 0.44c | N/Ac | N/Ac | ||
rs5219 | 0.46a | 0.14a N/Ab |
0.38a 3.2b |
0.38a 3.7b |
0.23a 28.7b |
0.26a 19.7b |
0.42a 1.1b |
0.33a 9.2b |
0.01a N/Ab |
0.41a 1.24b |
0.29a 17.4b |
0.00a N/Ab |
0.06a N/Ab |
N/Ac | 0.07c | 0.05c | 8e-8c | 1e-5c | 0.29c | 0.002c | N/Ac | 0.26c | 3e-5c | N/Ac | N/Ac | ||
rs4149056 | 0.04a | 0.06a | 0.15a | 0.14a | 0.14a | 0.14a | 0.02a | 0.12a | 0.02a | 0.08a | 0.21a | 0.01a | 0.02a |
0.38b | 3.0b | 2.19b | 2.4b | 2.6b | 8.5b | 1.1b | 7.9b | 0.05b | 11.0b | 13.3b | 7.6b | ||
0.53c | 0.08c | 0.14c | 0.12c | 0.10c | 0.004c | 0.29c | 0.004c | 0.82c | 0.001c | 3e-4c | 0.01c | ||
rs7294 | 0.38a | 0.48a | 0.31a | 0.04a | 0.17a | 0.42a | 0.67a | 0.09a | 0.43a | 0.35a | 0.34a | 0.51a | 0.46a |
N/Ab | 14.5b | 0.64b | 0.98b | 15.2b | 0.02b | 2.9b | N/Ab | 23.4b | 10.7b | N/Ab | N/Ab | ||
N/Ac | 1e-4c | 0.42c | 0.32c | 1e-4c | 0.89c | 0.09c | N/Ac | 1e-6c | 0.001c | N/Ac | N/Ac | ||
rs9934438 | 0.41a | 0.15a | 0.43a | 0.96a | 0.82a | 0.36a | 0.17a | 0.90a | 0.04a | 0.47a | 0.48a | 0.03a | 0.06a |
27.3b | 0.19b | N/Ab | N/Ab | 1.4b | 32.2b | N/Ab | N/Ab | 1.3b | 2.4b | N/Ab | N/Ab | ||
1.7e-7c | 0.65c | N/Ac | N/Ac | 0.24c | 1e-8c | N/Ac | N/Ac | 0.25c | 0.12c | N/Ac | N/Ac | ||
rs12659 | 0.49a | 0.40a | 0.42a | 0.49a | 0.53a | 0.39a | 0.36a | 0.54a | 0.53a | 0.34a | 0.44a | 0.48a | 0.55a |
2.8b | 2.5b | 0.02b | 0.81b | 4.8b | 8.3b | 1.4b | 0.77b | 8.1b | 1.2b | 0.05b | 1.8b | ||
0.09c | 0.10c | 0.90c | 0.37c | 0.03c | 0.004c | 0.23c | 0.38c | 0.004c | 0.28c | 0.83c | 0.18c | ||
rs1051266 | 0.48a | 0.43a | 0.57a | 0.52a | 0.46a | 0.60a | 0.60a | 0.46a | 0.31a | 0.65a | 0.55a | 0.33a | 0.31a |
0.79b | 3.9b | 0.92b | 0.17b | 4.6b | 7.9b | 0.31b | 15.2b | 10.3b | 2.5b | 12.4b | 14.1b | ||
0.37c | 0.05c | 0.33c | 0.68c | 0.01c | 0.005c | 0.58c | 1e-4c | 0.001c | 0.11c | 4e-4c | 2e-4c | ||
rs1131596 | 0.47a | 0.38a | 0.57a | 0.52a | 0.46a | 0.60a | 0.61a | 0.46a | 0.24a | 0.65a | 0.55a | 0.28a | 0.28a |
3.1b | 5.1b | 1.5b | 0.03b | 7.8b | 9.6b | 0.09b | 28.3b | 11.8b | 3.5b | 201b | 19.0b | ||
0.08c | 0.02c | 0.22c | 0.87c | 0.005c | 0.001c | 0.77c | 1.1e-7c | 0.001c | 0.06c | 1e-5c | 1e-5c | ||
rs4124874 | 0.44a | 0.22a | 0.57a | 0.72a | 0.55a | 0.62a | 0.39a | 0.69a | 0.11a | 0.48a | 0.56a | 0.09a | 0.22a |
47.3b | 7.8b | 42.7b | 5.6b | 15.4b | 1.1b | 31.5b | 63.9b | 0.74b | 7.04b | 74.6b | 0.9b | ||
N/Ac | 0.005c | N/AC | 0.02c | 9e−5 c | 0.28c | 2e−8 c | N/Ac | 0.38c | 008e−3 c | N/A c | 0.3c | ||
rs10929302 | 0.35a | 0.33a | 0.30a | 0.11a | 0.15a | 0.23a | 0.44a | 0.18a | 0.36a | 0.34a | 0.24a | 0.64a | 0.30a |
0.183b | 0.95b | 37.5b | 23.4b | 7.7b | 4.1b | 18.5b | 0.05 b | 0.01b | 7.7b | 0.08b | 0.9b | ||
0.67c | 0.33c | N/Ac | 2e−6 c | 5e−3 c | 0.04c | 2e−5 c | 0.83c | 0.91c | 6e−3 c | 0.78c | 0.32c | ||
rs4148323 | 0.0a | 0.01a | 0.0a | 0.23a | 0.10a | 0.0a | 0.02a | 0.13a | 0.0a | 0.02a | 0.0a | 0.0a | 0.0a |
2.7b | N/Ab | 82.9b | 35.2b | N/Ab | 6.4b | 45.3b | N/Ab | 7.8b | N/Ab | N/Ab | N/Ab | ||
0.09c | N/Ac | N/Ac | N/Ac | N/Ac | 0.01c | N/Ac | N/Ab | 5e−3 c | N/Ac | N/Ac | N/Ac | ||
rs4680 | 0.50a | 0.27a | 0.46a | 0.31a | 0.26a | 0.52a | 0.43a | 0.28a | 0.28a | 0.39a | 0.45a | 0.30a | 0.36a |
19.0b | 0.6b | 17.6b | 26.1b | 0.3b | 2.0b | 24.5b | 22.8b | 3.8b | 1.1b | 20.2b | 15.4b | ||
1e−5 c | 0.43c | 3e-5 c | 3.1e-7 c | 0.55c | 0.15c | 7.2e-7 c | 1e-6c | 0.05c | 0.28c | 6e-6 c | 8e-5 c | ||
rs1695 | 0.30a | 0.45a 10.2b |
0.39a 5.1b |
0.18a 8.6b |
0.22a 3.6b |
0.31a 0.2b |
0.31a 0.01b |
0.10a 28.7b |
0.51a 23.7b |
0.56a 27.6b |
0.29a 23.7b |
0.39a 5.8b |
0.43a 10.3b |
0.001c | 0.02c | 0.003c | 0.05c | 0.62c | 0.76c | 8e-8 c | 1e-6 c | 1.5e-7c | 1e-6 c | 0.01c | 0.001c | ||
rs1138272 | 0.10a | 0.00a | 0.09a | 0.00a | 0.00a | 0.05a | 0.08a | 0.00a | 0.01a | 0.05a | 0.05a | 0.00a | 0.001a |
6.4b | N/A | 21.1b | 19.1b | 2.6b | 0.2b | N/Ab | 13.2b | 2.07b | 3.6b | 22.1b | 17.1b | ||
0.01c | N/A | 4e-6c | 1e-5c | 0.1c | 0.58c | N/Ac | 3e-4c | 0.15c | 0.05c | 2e-6c | 3e-5c | ||
rs890293 | 0.07a | 0.16a | 0.05a | 0.04a | 0.02a | 0.05a | 0.05a | 0.02a | 0.14a | 0.03a | 0.05a | 0.15a | 0.10a |
10.1b | 0.5b | 1.2b | 6.5b | 0.6b | 0.4b | 4.8b | 7.3b | 2.1b | 0.5b | 10.8b | 2.3b | ||
0.001c | 0.46c | 0.27C | 0.01c | 0.44 c | 0.54c | 0.02 c | 0.007c | 0.14c | 0.47 c | 0.001 c | 0.12c | ||
rs10264272 | 0.0a | 0.05a | 0.00a | 0.00a | 0.00a | 0.00a | 0.00a | 0.0a | 0.24a | 0.02a | 0.01a | 0.17a | 0.11a |
16.5b | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | 7.8b | 1.6b | N/Ab | N/Ab | ||
5e−5 c | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | 0.005c | 0.21c | N/Ac | N/Ac | ||
rs776746 | 0.03a | 0.68a | 0.04a | 0.31a | 0.31a | 0.05a | 0.28a | 0.25a | 0.88a | 0.23a | 0.05a | 0.83a | 0.75a |
N/Ab | 0.4b | N/Ab | N/Ab | 1.9b | N/Ab | N/Ab | N/Ab | N/Ab | 1.5b | N/Ab | N/Ab | ||
N/Ac | 0.52c | N/Ac | N/Ac | 0.16c | N/Ac | N/Ac | N/Ac | N/Ac | 0.21c | N/Ac | N/Ac | ||
rs4986913 | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.005a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a |
N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | 1.6b | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | ||
N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | 0.20c | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | ||
rs4986910 | 0.0a | 0.0a | 0.01a | 0.0a | 0.0a | 0.01a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a |
N/Ab | 3.6b | N/Ab | N/Ab | 3.6b | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | ||
N/Ac | 0.06c | N/Ac | N/Ac | 0.06c | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | ||
rs2740574 | 0.004a | 0.67a | 0.02a | 0.0a | 0.0a | 0.03a | 0.08a | 0.0a | 0.83a | 0.07a | 0.03a | 0.76a | 0.66a |
N/Ab | 2.4b | 0.6b | 0.6b | 7.8b | 23.2b | 0.6b | N/Ab | 19.7b | 6.4b | N/Ab | N/Ab | ||
N/Ac | 0.12c | 0.43c | 0.45c | 0.005c | 1.4e-6b | 0.43c | N/Ac | 1e-5c | 0.01c | N/Ac | N/Ac | ||
rs4986893 | 0.0a | 0.0a | 0.0a | 0.04a | 0.07a | 0.0a | 0.0a | 0.07a | 0.01a | 0.0a | 0.0a | 0.0a | 0.005a |
N/Ab | N/Ab | 14.7b | 25.6b | N/Ab | N/Ab | 30.8b | 3.4b | N/Ab | N/Ab | N/Ab | 1.7b | ||
N/Ac | N/Ac | 1.4e-4c | 4e-7c | N/Ac | N/Ac | 3e-8c | 0.07c | N/Ac | N/Ac | N/Ac | 0.19c | ||
rs4244285 | 0.09a | 0.14a | 0.13a | 0.33a | 0.26a | 0.14a | 0.33a | 0.32a | 0.21a | 0.12a | 0.09a | 0.17a | 0.15a |
2.3b | 2.2b | N/Ab | 27.6b | 3.3b | N/Ab | N/Ab | 15.7b | 1.2b | 0.02b | 7.2b | 4.5b | ||
0.12c | 0.13c | N/Ac | 1.5e-7c | 0.07c | N/Ac | N/Ac | 8e-5c | 0.27c | 0.9c | 0.007c | 0.03c | ||
rs1799853 | 0.02a | 0.04a | 0.15a | 0.0a | 0.0a | 0.08a | 0.05a | 0.0a | 0.0a | 0.10a | 0.15a | 0.0a | 0.03a |
0.9b | 30.3b | 5.0b | 4.5b | 10.7b | 2.3b | 5.1b | 4.8b | 12.7b | 31.7b | 5.2b | 0.02b | ||
0.34c | 4e-8c | 0.02c | 0.03c | 0.001c | 0.12c | 0.02c | 0.02c | 4e-4c | 2e-8c | 0.02c | 0.89c | ||
rs28399454 | 0.0a | 0.07a 24.9b |
0.0a N/Ab |
0.0a N/Ab |
0.0a N/Ab |
0.0a N/Ab |
0.0a N/Ab |
0.0a N/Ab |
0.06a 18.8b |
0.0a N/Ab |
0.0a N/Ab |
0.13a N/Ab |
0.15a N/Ab |
5.8e-7c | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | 1e-5c | N/Ac | N/Ac | N/Ac | N/Ac | ||
rs1801272 | 0.0a | 0.01a | 0.04a | 0.0a | 0.0a | 0.03a | 0.01a | 0.0a | 0.0a | 0.0a | 0.05a | 0.0a | 0.0a |
2.7b | 11.8b | N/Ab | N/Ab | 9.2b | 3.2b | N/Ab | N/Ab | N/Ab | 15.8b | N/Ab | N/Ab | ||
0.09c | 6e-4c | N/Ac | N/Ac | 0.002c | 0.07c | N/Ac | N/Ac | N/Ac | 7e-5c | N/Ac | N/Ac | ||
rs28399433 | 0.09a | 0.06a | 0.05a | 0.27a | 0.18a | 0.04a | 0.19a | 0.28a | 0.09a | 0.10a | 0.06a | 0.10a | 0.06a |
0.2b | 3.0b | 28.7b | 8.0b | 3.9b | 10.5b | 32.2b | 0.002b | 0.1b | 1.2b | 0.1b | 1.4b | ||
0.64c | 0.08c | 8e-8c | 0.01c | 0.04c | 0.001c | 1e-8c | 0.96c | 0.75c | 0.27c | 0.70c | 0.23c | ||
rs3745274 | 0.31a | 0.35a | 0.28a | 0.27a | 0.33a | 0.23a | 0.23a | 0.22a | 0.36a | 0.31a | 0.30a | 0.40a | 0.38a |
0.05b | 0.6b | 15.5b | 0.1b | 3.8b | 4.6b | 5.3b | 1.2b | N/Ab | 0.04b | 4.7b | 2.5b | ||
0.82c | 0.40c | 8.4e-5c | 0.71c | 0.05c | 0.03c | 0.02c | 0.27c | N/Ac | 0.83c | 0.03c | 0.11c | ||
rs28399499 | 0.0a | 0.1a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.06a | 0.08a | 0.0a | 0.12a | 0.05a |
33.5b | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | 20.6b | 2.5b | N/Ab | N/Ab | 32.2b | ||
1e-8c | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | 6e-6c | 0.11c | N/Ac | N/Ac | 1e-8c | ||
rs59421388 | 0.0a | 0.04a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.09a | 0.0a | 0.0a | 0.11a | 0.08a |
13.7b | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | ||
2e-4c | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | ||
rs28371725 | 0.14a | 0.02a | 0.12a | 0.03a | 0.08a | 0.07a | 0.15a | 0.01a | 0.03a | 0.02a | 0.14a | 0.01a | 0.05a |
14.8b | 0.5b | 16.8b | 4.4b | 5.9b | 0.002b | 30.1b | 17.6b | 15.8b | N/Ab | 28.7b | 11.8b | ||
1e-4c | 0.46c | 4e-5c | 0.03c | 0.01c | 0.96c | 4e-8c | 3e-5c | 7e-5c | N/Ac | 8e-8c | 6e-4c | ||
rs61736512 | 0.0a | 0.04a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.17a | 0.0a | 0.0a | 0.11a | 0.09a |
13.7b | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | 32.2b | ||
2e-4c | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | 1e-8c | ||
rs28371706 | 0.0a | 0.15a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.0a | 0.19a | 0.0a | 0.0a | 0.25a | 0.20a |
N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | N/Ab | ||
N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | N/Ac | ||
rs5030656 | 0.0a | 0.01a | 0.02a | 0.0a | 0.0a | 0.04a | 0.0a | 0.0a | 0.0a | 0.01a | 0.01a | 0.0a | 0.0a |
2.7b | 6.8b | N/Ab | N/Ab | 13.0b | N/Ab | N/Ab | N/Ab | 2.6b | 11.0b | N/Ab | N/Ab | ||
0.99c | 0.01c | N/Ac | N/Ac | 3e-4c | N/Ac | N/Ac | N/Ac | 0.11c | 0.001c | N/Ac | N/Ac |
Notes: aMinor allele frequency, bChi-square value, cp-value, when p-value < 0.05 is considered a significant difference. CHE: Chechens from Jordan, ASW: African ancestry in Southwest USA, CEU: Utah, USA residents with Northern and Western European ancestry from the CEPH collection, CHB: Han Chinese in Beijing, China, CDX: Chinese Dai in Xishuangbanna, China, GIH: Gujarati Indians in Houston, Texas, USA, GBR: British in England and Scotland, JPT: Japanese in Tokyo, Japan, LWK: Luhya in Webuye, Kenya, MXL: Mexican ancestry in Los Angeles, California, USA, TSI: Toscani in Italy, YRI: Yoruba in Ibadan, Nigeria, ACB; African Caribbeans in Barbados.
Abbreviation: N/A, not applicable.