Table 2.
Model-Adjusted Risks of In-Hospital Death, Hospital Discharge, and CT scan Improvement
Outcome | Analyzed Categories | Model Type | Estimate (95% CI) |
|
---|---|---|---|---|
Early IFN versus No IFN | Late IFN versus No IFN | |||
In-hospital mortality(odds ratio) | all | logistic regressiona | 0.05 (0.01–0.37)p = 0.004 | 6.82 (1.14–40.8)p = 0.035 |
In-hospital mortality(hazard ratio) | all | Cox proportional hazardsb | 0.10 (0.02–0.50)p = 0.005 | 2.30 (0.64–8.27)cp = 0.203 |
Hospital discharge (hazard ratio) | survivors | Cox proportional hazardsa | 1.14 (0.93–1.41)cp = 0.213 | 0.69 (0.44–1.08)p = 0.101 |
CT scan improvement(hazard ratio) | survivors | Cox proportional hazardsa | 1.00 (0.81–1.22)cp = 0.975 | 0.50 (0.32–0.80)p = 0.004 |
Abbreviation: IFN, interferon α-2b.
Model adjusted for gender, age, hypertension, diabetes, oxygen saturation at admission, symptom onset to admission >7 days, plus symptom count at admission.
Model adjusted for gender, age, hypertension, diabetes, oxygen saturation at admission, and symptom onset to admission >7 days.
Proportional hazard assumption not met.