Table 1.
Clinical characteristic of the DM-ILD patients and healthy controls
| Variables | Healthy Controls (n = 30) | DM without ILD (n = 14) | DM-ILD (n = 40) |
|---|---|---|---|
| Age at onset (years), mean ± SD | 45.4 ± 10.3 | 52.6 ± 19.9 | 50.1 ± 13.3 |
| Gender (female/male) | 19/11 | 11/3 | 27/13 |
| Subtype of DM (DM/CADM) | 12/2 | 18/22 | |
| Subtype of ILD | |||
| A/SIP in all | 17 | ||
| CIP in all | 13 | ||
| Pulmonary function tests | |||
| HRCT score | 144.5 ± 37.21 | ||
| %FVC (%) | 84.2 ± 14.6 | 67.2 ± 19.6 | |
| %DLCO (%) | 52.0 ± 26.3 | 37.4 ± 18.5 | |
| Laboratory findings | |||
| CRP (mg/dL) | 4.1 ± 3.0 | 5.9 ± 5.4 | 13.5 ± 15.5 |
| ESR (mm/h) | 7.7 ± 6.0 | 20.6 ± 14.4 | 24.9 ± 21.5 |
| Ferritin (ng/mL) | 172.6 ± 147.5 | 238.0 ± 244.7 | 758.7 ± 1036.7 |
| CK (U/l) | 75.3 ± 29.2 | 100.0 ± 49.3 | 152.3 ± 204.7 |
aA/SIP Acute/subacute interstitial pneumonia, CADM clinically amyopathic dermatomyositis, CIP Chronic interstitial pneumonia, CK creatine kinase, CRP C-reactive protein, DLCO% % diffusing capacity of the lungs for carbon monoxide, DM dermatomyositis, ESR erythrocyte sedimentation rate, FVC% % forced vital capacity, HRCT high-resolution computed tomography, ILD interstitial lung disease