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. 2020 Jul 17;11:298. doi: 10.1186/s13287-020-01817-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Changes in the fat, liver, and pancreases in T2D mice. a Micrographs of the fat, liver, and pancreas from age-matched C57BL/6 control and T2D mice. b Weights of the fat, liver, and pancreas in C57BL/6 and T2D mice. c, e, g H&E stain of the fat tissue, liver, and pancreas of C57BL/6 and T2D mice. d Average size of the fat bubble in adipose tissue. f Quantification of fat bubble size in liver tissue. h Quantification islet area within each pancreas tissue. At least 5 mice were included in each group. *P < 0.05; **P < 0.01, ANOVA test