Table 1.

Clinicopathological characteristics of C1/2 molecular subtypes

TCGA	level	C1	C2	p	test
n		61	19
age (%)	Age < 60	27 (44.3)	9 (47.4)	1.000	Chisq Test
	Age > =60	34 (55.7)	10 (52.6)
gender (%)	FEMALE	25 (41.0)	10 (52.6)	0.529	Chisq Test
	MALE	36 (59.0)	9 (47.4)
M (%)	m0	39 (66.1)	12 (63.2)	0.972	Chisq Test
	m1	3 (5.1)	1 (5.3)
	mx	17 (28.8)	6 (31.6)
N (%)	n0	40 (65.6)	12 (66.7)	1.000	Chisq Test
	nx	21 (34.4)	6 (33.3)
T (%)	t2	9 (14.8)	5 (26.3)	0.225	Chisq Test
	t3	23 (37.7)	9 (47.4)
	t4	29 (47.5)	5 (26.3)
stage (%)	N/A	1 (1.6)	0 (0.0)	0.238	Chisq Test
	Stage II	26 (42.6)	13 (68.4)
	Stage III	31 (50.8)	5 (26.3)
	Stage IV	3 (4.9)	1 (5.3)
histological_type (%)	Epithelioid Cell	10 (16.4)	3 (15.8)	0.888	Chisq Test
	Spindle Cell	22 (36.1)	8 (42.1)
	Spindle Cell|Epithelioid Cell	29 (47.5)	8 (42.1)
vital_status (%)	ALIVE	41 (67.2)	16 (84.2)	0.255	Chisq Test
	DEAD	20 (32.8)	3 (15.8)
subtype (%)	subtype1	5 (8.2)	10 (52.6)	0.000	Chisq Test
	subtype2	17 (27.9)	6 (31.6)
	subtype3	21 (34.4)	1 (5.3)
	subtype4	18 (29.5)	2 (10.5)
chromosome.3.status (%)	Disomy 3	22 (36.1)	16 (84.2)	0.001	Chisq Test
	Monosomy 3	39 (63.9)	3 (15.8)
GEO	level	C1	C2	p	test
n		15	13
Age (%)	Age < 60	8 (53.3)	4 (30.8)	0.412	Fisher exact test
	Age > =60	7 (46.7)	9 (69.2)
vital_status (%)	ALIVE	10 (66.7)	2 (15.4)	0.019	Fisher exact test
	DEAD	5 (33.3)	11 (84.6)
Chromosome.3.status (%)	Disomy 3	11 (73.3)	3 (23.1)	0.023	Fisher exact test
	Monosomy 3	4 (26.7)	10 (76.9)
Metastasis (%)	No	11 (73.3)	4 (30.8)	0.061	Fisher exact test
	Yes	4 (26.7)	9 (69.2)

M Metastasis, N Lymph Node, T Tumor size