Table 4.

Depicting Odd Ratio (OR) and corresponding p-value of selected gene polymorphisms with CAD

MODEL	OR (95% CI)	p-value
ESR1 IVS1–397 T/C
Co-dominant
TC vs TT	1.05 [0.79–1.41]	0.7
CC vs TT	1.17 [0.73–1.88]	0.5
Dominant
TC + CC vs TT	1.07 [0.81–1.42]	0.6
Recessive
CC vs TC + TT	3.39 [0.92–12.42]	0.6
Allelic
C vs T	1.07 [0.87–1.31]	0.5
ESR1- IVS1–351 A/G
Co-dominant
AG vs AA	1.23 [0.89–1.70]	0.2
GG vs AA	1.93 [1.29–2.89]	0.001*
Dominant
AG + GG vs AA	1.40 [1.03–1.90]	0.03*
Recessive
GG vs AG+ AA	1.70 [1.20–2.40]	0.003*
Allelic
G vs A	1.37 [1.12–1.67]	0.002*
CETP-(C277T) (TaqIB)
Co-dominant
B1B2 vs B2B2	1.13 [0.82–1.57]	0.4
B1B1 vs B2B2	1.25 [0.83–1.90]	0.3
Dominant
B1B2 + B1B1 vs B2B2	1.63 [0.85–1.59]	0.3
Recessive
B1B1 vs B1B2 + B2B2	1.16 [0.81–1.64]	0.4
Allelic
B1 vs B2	1.11 [0.91–1.35]	0.3
MTHFR C677T
Co-dominant
CT vs CC	4.61 [2.20–9.67]	0.00001*
TT vs CC	Not possible†	–
Dominant
CT + TT vs CC	Not possible†	–
Recessive
TT vs CT + CC	Not possible†	–
Allelic
T vs C	5.36 [2.45–10.62]	< 0.0001*
MTHFR G1793A
Co-dominant
GA vs GG	1.29 [0.91–1.83]	0.15
AA vs GG	Not possible†	–
Dominant
GA + AA vs GG	Not possible†	–
Recessive
AA vs GA+ GG	Not possible†	–
Allelic
A vs G	1.37 [1.00–1.90]	0.06
MS A2756G
Co-dominant
AG vs AA	1.58 [1.16–2.14]	0.003*
GG vs AA	3.90 [1.06–14.34]	0.03*
Dominant
AG + GG vs AA	1.64 [1.22–2.22]	0.001*
Recessive
GG vs AG+ AA	3.39 [0.93–12.42]	0.1
Allelic
G vs A	1.57 [1.20–2.05]	0.001*

* Significant values