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. 2020 Jul 17;21:284. doi: 10.1186/s12882-020-01935-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Regional association plot of ANGPT2 region with acute kidney injury sub-phenotype 2 (AKI-SP2). Results are plotted as genomic locus versus –log (P value) for the association with AKI-SP2. The P value reflects an additive genetic model for association with AKI-SP2. Each locus is also annotated with the background genome recombination rate. Underneath the regional association plot is a schematic of the ANGPT2 and MCPH1 genes with exons represented as vertical red lines. The top single nucleotide polymorphism (SNP) was rs2920656. Plot was generated using Goldenhelix based on RefSeq Genes 105v2 in the CEU population, a Utah population of European ancestry