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. 2020 Jul 17;21:284. doi: 10.1186/s12882-020-01935-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — ANG-2 concentrations by rs2920656 genotype in human microvascular kidney endothelial cells (HKMECs). Of 8 human kidney samples, 2 were CC, 5 were CT and 1 was TT for rs2920656. The T allele of rs2920656 was associated with decreased ANG-2 concentrations. Student t-test was used combining the CT and TT genotypes and generated a p-value = 0.07 for the difference between genotypes and ANG-2 concentrations. The mean ANG-2 concentrations are 315,000 pg/mL for CC, 220,900 pg/mL for CT and TT