Skip to main content
. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Biol Psychiatry. 2020 Feb 8;88(3):224–235. doi: 10.1016/j.biopsych.2020.01.025

Figure 4.

Figure 4.

SZ effects on mortality, mitotic, and chronological age clocks are independent. (A) Correlation plot using biweight correlation between all measures for pooled data, adjusted based on study. Age residuals are used for variables that show robust age correlations (epigenetic clocks, proteins, smoking pack-years). Variables are ordered based on hierarchical clustering. Study-specific plots are found in Figure S13. (B-D) First six principal components, only showing variables with loadings higher than expected by chance. (E) PC correlations with SZ and sex for pooled data sets, and with SZ and antipsychotic classes for CF males. CF females are shown in Figure S18. Multiple regression analyses are shown in Table S21.