Table 3.

Odds of Mortality With AKI in Patients Hospitalized With Coronavirus Disease 2019^a,b

Demographic and Clinical Characteristics	Age- and Sex-Adjusted Odds	P	Multivariable Analysis	P
AKI
Stage 1	2.7 (1.4-5.2)	.003	2.8 (1.002-7.8)	.049c
Stage 2	5.1 (2.4-10.9)	<.001	3.3 (1.05-10.5)	.04c
Stage 3	9.2 (4.6-18.3)	<.001	4.8 (1.6-14.5)	.01c
ARDS	38.1 (17.4-83.4)	<.001	32.6 (12.8-83.6)	<.001c
Demographic characteristics
Age	—	—	1.06 (1.03-1.1)	<.001c
Male sex (vs female)	—	—	1.5 (0.7-3.3)	.3
Race (vs white)	—	—	—	—
African American	0.8 (0.5-1.4)	.5	0.4 (0.2-1.1)	.08
Hispanic	1.5 (0.7-2.9)	.3	0.6 (0.2-2.1)	.4
Other	0.6 (0.2-1.3)	.2	0.5 (0.1-1.9)	.3
Nursing home admit (vs home)	1.4 (0.8-2.3)	.3	—	—
Insurance (vs Medicare)	—	—	—	—
Medicaid	1.4 (0.6-3.4)	.5	—	—
Private	0.7 (0.4-1.2)	.2	—	—
Other	0.8 (0.2-3.2)	.8	—	—
Comorbid condition
Hypertension	1.1 (0.7-1.8)	.7	0.6 (0.2-1.3)	.2
Diabetes mellitus	1.3 (0.8-2.1)	.2	1.1 (0.5-2.3)	.9
Hyperlipidemia	1.4 (0.8-2.2)	.2	—	—
Cardiac disease	1.1 (0.7-1.9)	.7	1.7 (0.7-3.9)	.2
Chronic kidney disease	0.8 (0.4-1.6)	.5	—	—
Chronic obstructive pulmonary disease	0.7 (0.4-1.4)	.3	—	—
Stroke or dementia	1.1 (0.6-1.9)	.7	—	—
Smoking	0.8 (0.4-1.5)	.5	—	—
Malignancy	1.2 (0.7-2.1)	.5	—	—
BMI class (kg/m2), (vs normal, 18.5-24.9)	—	—	—	—
Overweight, 25-29.9	1.8 (1.01-3.3)	.047	1.9 (0.7-5.5)	.2
Obese, ≥30	2.2 (1.1-4.1)	.02	1.6 (0.6-4.3)	.4
Underweight <18.5	1.3 (0.3-5.4)	.8	1.3 (0.1-14.9)	.8

^aAKI = acute kidney injury; ARDS = acute respiratory distress syndrome, BMI = body mass index.

^bOdds adjusted for AKI, ARDS, and BMI class in addition to 6 essential covariates (age, sex, race, hypertension, diabetes, and cardiac disease).

^cStatistically significant.