Table 1.
Patient Characteristics Stratified by Month of COVID-19 Convalescent Plasma Transfusiona
| April | May | Total | |
|---|---|---|---|
| Characteristic | |||
| N | 6214 | 13,786 | 20,000 |
| Age, y | |||
| 18-39 | 449 (7.2) | 1083 (7.9) | 1,532 (7.7) |
| 40-59 | 2056 (33.1) | 4320 (31.3) | 6,376 (31.9) |
| 60-69 | 1798 (28.9) | 3611 (26.2) | 5,409 (27.0) |
| 70-79 | 1260 (20.3) | 2859 (20.7) | 4,119 (20.6) |
| ≥80 | 651 (10.5) | 1913 (13.9) | 2,564 (12.8) |
| Sex | |||
| Female | 2262 (36.4) | 5499 (39.9) | 7761 (38.8) |
| Male | 3924 (63.2) | 8241 (59.8) | 12,165 (60.8) |
| Intersex or transgender | 22 (0.4) | 35 (0.3) | 57 (0.3) |
| Undisclosed | 6 (0.1) | 11 (0.1) | 17 (0.1) |
| Weight statusb | |||
| Underweight | 61 (1.2) | 249 (1.8) | 310 (1.7) |
| Normal weight | 868 (17.3) | 2454 (18.0) | 3322 (17.8) |
| Overweight | 1502 (30.0) | 3802 (27.8) | 5304 (28.4) |
| Obese | 2587 (51.6) | 7166 (52.4) | 9753 (52.2) |
| Race | |||
| Asian | 408 (6.6) | 591 (4.3) | 999 (5.0) |
| Black | 1132 (18.2) | 2784 (20.2) | 3916 (19.6) |
| White | 2993 (48.2) | 6741 (48.9) | 9734 (48.7) |
| Other or unknown | 1681 (27.1) | 3670 (26.6) | 5351 (26.8) |
| Ethnicity | |||
| Hispanic or Latino | 2142 (34.5) | 4794 (34.8) | 6936 (34.7) |
| Not Hispanic or Latino | 4072 (65.5) | 8992 (65.2) | 13,064 (65.3) |
| Clinical status | |||
| Current severe or life-threatening COVID-19 | 4963 (79.9) | 9274 (67.3) | 14,237 (71.2) |
| High risk of severe or life-threatening COVID-19 | 1251 (20.1) | 4512 (32.7) | 5763 (28.8) |
| Intensive care unit admission | 4038 (65.0) | 7522 (55.0) | 11,560 (58.1) |
| Mechanical ventilationc | 2709 (48.5) | 4155 (30.4) | 6864 (35.6) |
| Clinical symptomsd | |||
| Respiratory failure | 3574 (72.0) | 6155 (66.4) | 9729 (68.3) |
| Dyspnea | 3152 (63.5) | 6561 (70.7) | 9713 (68.2) |
| Blood oxygen saturation ≤93% | 3092 (62.3) | 6663 (71.8) | 9755 (68.5) |
| Lung infiltrates >50% within 24 to 48 h | 2105 (42.4) | 4021 (43.4) | 6126 (43.0) |
| Respiratory frequency ≥30/min | 1937 (39.0) | 4014 (43.3) | 5951 (41.8) |
| PaO2:FiO2e <300 | 1642 (33.1) | 3014 (32.5) | 4656 (32.7) |
| Multiple organ dysfunction or failure | 936 (18.9) | 1212 (13.1) | 2148 (15.1) |
| Septic shock | 734 (14.8) | 987 (10.6) | 1721 (12.1) |
a
Values shown are n (%).
b
These data include a subset of the sample (n=18,689).
c
These data include a subset of the sample (n=19,256).
d
These data include a subset of the sample (n=14,237), only those patients that currently have severe or life-threatening COVID-19.
e
PaO2:FiO2 the ratio of partial pressure of arterial oxygen to fraction of inspired oxygen ratio.