Figure 1.

Rats administered with high concentration of ceftriaxone and calcium developed AKI. (a) Concentrations of blood urea nitrogen (mg/dL). (b) Concentrations of creatinine (mg/dL) (n = 10 for each group; the results are expressed as mean ± SD; ^∗∗P < 0.01 compared with the control group). (c, d) Representative H&E-stained kidney sections ((c) NC group; (d) group 1, bars = 50 μm). Injury scores were 1 and 4, respectively. The arrows indicated the representative morphological changes including severe interstitial edema, cellular infiltrate, tubular cell swelling, and necrosis.