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Ceftriaxone calcium crystals promoted NLRP3 inflammasome activation and oxidative stress injury in vitro. (a, b) mRNA levels of NLRP3 (a) and IL-1β (b) in vitro. (c) Concentrations of MDA in vitro. (d) Concentrations of H2O2 in vitro (the results are expressed as mean ± SD; ∗P < 0.05 compared with the control group, ∗∗P < 0.01 compared with the control group).
