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. Author manuscript; available in PMC: 2020 Jul 19.
Published in final edited form as: Nat Med. 2019 Jun 24;25(7):1104–1109. doi: 10.1038/s41591-019-0485-4

Extended Data 1:

Extended Data 1:

A: Histogram of two-sided p-values (Wald-Z tests) for time coefficient from LOOCV models predicting 16S Veillonella abundance. Red line represents p value for model trained without any hold outs. B: Histogram of two-sided p-values for time coefficient from 1000 label permutations in GLMM models predicting Veillonella relative abundance. Red line represents p value for model trained without any label permutation.