Table 3.
Univariate and multivariate analysis of prognostic factors in overall survival
| Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| Variable | HR | 95.0% CI | P value | HR | 95.0% CI | P value | ||
|
Age (y) ≤55 vs. > 55 |
1.606 | 0.844 | −3.058 | 0.149 | – | – | – | – |
|
Postoperativeresidual disease Microscopic vs. Macroscopic |
5.811 | 3.019 | −11.182 | P < 0.001 | 4.300 | 2.124 | −8.703 | P < 0.001 |
|
Grade Low vs. High |
2.695 | 1.225 | −5.928 | 0.014 | 1.714 | 0.733 | −4.004 | 0.214 |
|
Stage I or II vs. III or IV |
2.972 | 1.195 | −7.393 | 0.019 | 1.799 | 0.656 | −4.930 | 0.254 |
|
Plateletcount (1000/μl) ≤300 vs. > 300 |
2.298 | 1.208 | −4.373 | 0.011 | 2.363 | 1.202 | −4.645 | 0.013 |
|
Platelet count reduction > 25% vs. ≤25% |
2.222 | 1.200 | −4.113 | 0.011 | 2.363 | 1.262 | −4.423 | 0.007 |
|
Plasmafibrinogen(g/l) 2–4 vs. > 4 |
1.092 | 0.573 | −2.083 | 0.789 | – | – | – | – |
|
Plasma D-dimer (mg/l) ≤0.3 vs. > 0.3 |
0.712 | 0.315 | −1.608 | 0.413 | – | – | – | – |
CI confidence interval, HR hazard ratio