Table 1.
Technology | Pathogen identification | Detection of antibiotic resistance | Antibiotic susceptibility testing with MIC | Turnaround time/time to result from patient blood | Turnaround time/time to result from positive blood culture |
---|---|---|---|---|---|
Singleplex PCR | Yes | No | No | NA | 1–3 h |
Multiplex PCR | Yes | Genotypic only | No | NA | 1–2 h |
NAAT/microarray | Yes | Genotypic only | No | NA | 2.5 h |
MALDI-TOF | Yes | No | No | NA | 24 h |
PNA-FISH | Yes | No | No | NA | 1 h |
T2MR assay | Yes | No | No | 3–5 h | NA |
Abbreviations: MALDI-TOF, matrix-assisted laser desorption ionization–time-of-flight; MIC, minimum inhibitory concentration; NA, not applicable; NAAT, nucleic acid amplification technology; PCR, polymerase chain reaction; PNA-FISH, peptide nucleic acid–fluorescence in situ hybridization.