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. Author manuscript; available in PMC: 2020 Jul 19.
Published in final edited form as: Annu Rev Anal Chem (Palo Alto Calif). 2019 Apr 2;12(1):41–67. doi: 10.1146/annurev-anchem-061318-115529

Table 1.

Summary of commercially available rapid identification/antibiotic susceptibility testing technologies for bloodstream infections. Adapted from Edmiston et al. (130)

Technology Pathogen identification Detection of antibiotic resistance Antibiotic susceptibility testing with MIC Turnaround time/time to result from patient blood Turnaround time/time to result from positive blood culture
Singleplex PCR Yes No No NA 1–3 h
Multiplex PCR Yes Genotypic only No NA 1–2 h
NAAT/microarray Yes Genotypic only No NA 2.5 h
MALDI-TOF Yes No No NA 24 h
PNA-FISH Yes No No NA 1 h
T2MR assay Yes No No 3–5 h NA

Abbreviations: MALDI-TOF, matrix-assisted laser desorption ionization–time-of-flight; MIC, minimum inhibitory concentration; NA, not applicable; NAAT, nucleic acid amplification technology; PCR, polymerase chain reaction; PNA-FISH, peptide nucleic acid–fluorescence in situ hybridization.